Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Polygodial (Tadeonal) 是一种抗真菌增效剂和抗生素。它是一种倍半萜,具有抗痛觉过敏的作用。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 461 | 现货 | ||
5 mg | ¥ 1,160 | 现货 | ||
10 mg | ¥ 1,730 | 现货 | ||
25 mg | ¥ 3,930 | 现货 | ||
50 mg | ¥ 5,680 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 997 | 现货 |
产品描述 | Polygodial (Tadeonal) is an antifungal potentiator and an antibiotic, particularly against Saccharomyces cerevisiae, Candida utilis, and Sclerotinia libertiana. |
体外活性 | When tested on S. cerevisiae, polygodial proved to be fungicidal rather than fungistatic. When the cells of S. cerevisiae are treated in vitro with polygodial for 10 min, the cell membrane becomes severely damaged, and many vesicles, possibly formed from the fragmented cell membrane, can be observed within the cytoplasm[1]. |
体内活性 | Polygodial (0.1 to 10 mg kg(-1), i.p.) produced significant inhibition of acetic acid, kaolin and zymosan-induced writhing in mice, being about 14 to 27-fold more potent than the hydroalcoholic extract at the ID50 level[2]. |
别名 | Tadeonal, 水蓼二醛 |
分子量 | 234.33 |
分子式 | C15H22O2 |
CAS No. | 6754-20-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/ml (277.39 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 4.2675 mL | 21.3374 mL | 42.6749 mL | 106.6872 mL |
5 mM | 0.8535 mL | 4.2675 mL | 8.535 mL | 21.3374 mL | |
10 mM | 0.4267 mL | 2.1337 mL | 4.2675 mL | 10.6687 mL | |
20 mM | 0.2134 mL | 1.0669 mL | 2.1337 mL | 5.3344 mL | |
50 mM | 0.0853 mL | 0.4267 mL | 0.8535 mL | 2.1337 mL | |
100 mM | 0.0427 mL | 0.2134 mL | 0.4267 mL | 1.0669 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Polygodial 6754-20-7 Microbiology/Virology Antifungal Inhibitor Tadeonal Antifungal,Potentiator,sesquiterpene,anti-hyperalgesic Poligodial 水蓼二醛 inhibit Fungal inhibitor