Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Phosalone 是一种有机磷酸盐化学品,通常用作杀虫剂和杀螨剂。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
500 mg | ¥ 415 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 221 | 现货 |
产品描述 | Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide. |
体内活性 | Phosalone (PLN) as a key member of OPs, to induce senescence in rat embryonic fibroblast (REF) cells and to demonstrate the beneficial effects of the known antioxidant ellagic acid (EA) in diminishing the PLN-induced toxic effects, the levels of cell viability, oxidative stress markers, inflammatory cytokines, telomerase activity, and the expression of the genes related to senescence were investigated. This accounts for the mechanistic approval of the role of OPs in induction of senescence in rat fibroblasts. Incorporation of EA diminished PLN toxicity mainly through suppression of p38 and p53 at gene and protein levels, and tempered the inflammation factors (TNF-α, IL-1β, IL-6 and NF-κB), which further affected cell division. |
分子量 | 367.81 |
分子式 | C12H15ClNO4PS2 |
CAS No. | 2310-17-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 41 mg/mL (111.47 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.7188 mL | 13.594 mL | 27.188 mL | 67.9699 mL |
5 mM | 0.5438 mL | 2.7188 mL | 5.4376 mL | 13.594 mL | |
10 mM | 0.2719 mL | 1.3594 mL | 2.7188 mL | 6.797 mL | |
20 mM | 0.1359 mL | 0.6797 mL | 1.3594 mL | 3.3985 mL | |
50 mM | 0.0544 mL | 0.2719 mL | 0.5438 mL | 1.3594 mL | |
100 mM | 0.0272 mL | 0.1359 mL | 0.2719 mL | 0.6797 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Phosalone 2310-17-0 Microbiology/Virology Parasite Inhibitor inhibit inhibitor