| 规格 | 库存 | 单价 | 数量 |
|---|---|---|---|
| 5 mg | 上海现货 | 209.00 |
|
| 10 mg | 上海现货 | 408.00 |
|
| 25 mg | 上海现货 | 688.00 |
|
| 50 mg | 上海现货 | 1317.00 |
|
| 100 mg | 上海现货 | 2217.00 |
|
| 200 mg | 待询 | 3427.00 |
|
生物活性
|
产品描述 |
Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium exerts its action by blocking the antigen-mediated calcium ion influx into mast cells. |
|
靶点活性 |
H1 receptor, |
|
体外活性 |
Pemirolast potassium 能够抑制感觉神经中多肽的释放（P物质,神经激肽(NK) A,以及CGRP）,并能够抑制组织肥大细胞释放化学介质, 常用于治疗过敏反应。 |
|
体内活性 |
在大鼠体内,Pemirolast potassium通过抑制感觉神经肽的释放,减弱对于紫杉醇的过敏反应,也能通过抑制P物质的释放减少对于高岭土的摄入. |
化学信息
|
分子量 |
266.31 |
|
分子式 |
C10H7KN6O |
|
CAS |
100299-08-9 |
|
溶解度 |
H2O: 200 mg/mL (751.03 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble ) |
|
储存条件 |
store at -80°C |
|
备注 |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. |
配制溶液
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.755 ml | 18.775 ml | 37.55 ml |
| 5 mM | 0.751 ml | 3.755 ml | 7.51 ml |
| 10 mM | 0.376 ml | 1.878 ml | 3.755 ml |
| 50 mM | 0.075 ml | 0.376 ml | 0.751 ml |
产品操作手册
