Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is a phenylbutazone derivative. It has an anti-inflammatory effect. Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
2 mg | ¥ 374 | 5日内发货 | ||
5 mg | ¥ 677 | 5日内发货 | ||
1 mL * 10 mM (in DMSO) | ¥ 1,090 | 5日内发货 |
产品描述 | Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is a phenylbutazone derivative. It has an anti-inflammatory effect. Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis. |
体外活性 | Oxyphenbutazone increases the anticancer efficiency of methotrexate (MTX) in Hep3B cells. Oxyphenbutazone has reparative effects in the hepatocytes. Oxyphenbutazone (2.5 -7.5 μM; 48 hours) co-treatment with (MTX, 0.25-1.0 μM) displays potential cytotoxicity against Hep3B cells[1]. |
体内活性 | When co-treatment with MTX (5.0 or 2.5 mg/kg/week; i.p.), Oxyphenbutazone (70 mg/kg/week; p.o.; in two divided doses; for 13 weeks) has potential anticancer activity [1]. |
分子量 | 324.37 |
分子式 | C19H20N2O3 |
CAS No. | 129-20-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Oxyphenbutazone 129-20-4 Immunology/Inflammation Neuroscience COX Inhibitor inhibitor inhibit