Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Octopamine hydrochloride ((±)-p-Octopamine hydrochlorid) 是一种与去甲肾上腺素结构相关的生物单胺类物质,在无脊椎动物中起着神经调节剂、神经激素和神经递质的作用。它对转染人 alpha2-肾上腺素受体(ARs)的中国仓鼠卵巢细胞 α2-ARs 有刺激作用。它提高糖原分解、糖酵解、糖异生、摄氧量和门脉灌注压。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
500 mg | ¥ 333 | 现货 | ||
1 g | ¥ 418 | 现货 | ||
5 g | ¥ 585 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 418 | 现货 |
产品描述 | Octopamine hydrochloride ((±)-p-Octopamine hydrochlorid) is a biogenic monoamine structurally associated with noradrenaline. It can serve as a neurohormone, a neurotransmitter, and a neuromodulator in invertebrates. |
体外活性 | Octopamine is present in relatively high concentrations in neuronal as well as in non-neuronal tissues of most invertebrate species studied, and modulates almost every physiological process. Octopamine acts as neurohormone including desensitization of sensory inputs, influence on learning and memory, or regulation of the mood of the animal in the central nervous system. Octopamine is the only neuroactive non-peptide transmitter whose physiological role is restricted to invertebrates, and all octopamine receptors belong to the family of G-protein coupled receptors. [1] |
体内活性 | Octopamine (10 mg/mL) is necessary for the acquisition of sugar memory in Drosophila. [2] Octopamine treatment increases responsiveness to brood pheromone and decreased responsiveness to social inhibition. Octopamine acts as an important source of variation in response thresholds and as a modulator of pheromonal communication in insect societies. [3] Octopamine (10 μM) injected into the mushroom body (MB) calyces or the antennal lobe but not the lateral protocerebral lobe produces a lasting, pairing-specific enhancement of extension of the proboscis. Octopamine (10 μM) injected into the MB calyces results in an additional pairing-specific effect, because it does not lead to an acquisition but a consolidation after conditioning. [4] Octopamine treatment significantly elevates levels of octopamine in the brain and caused a significant dose-dependent increase in the number of new foragers. Octopamine treatment is effective only when given to bees old enough to forage, i.e., older than 4 days of age. Octopamine influences division of labor in honey bee colonies. [5] |
别名 | 章鱼胺盐酸盐, (±)-p-Octopamine hydrochlorid, (+,-)-Octopamine HCl, 章胺盐酸盐 |
分子量 | 189.639 |
分子式 | C8H12ClNO2 |
CAS No. | 770-05-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 200.4 mM
H2O: 200.4 mM
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO / H2O | 1 mM | 5.2732 mL | 26.3659 mL | 52.7318 mL | 131.8294 mL |
5 mM | 1.0546 mL | 5.2732 mL | 10.5464 mL | 26.3659 mL | |
10 mM | 0.5273 mL | 2.6366 mL | 5.2732 mL | 13.1829 mL | |
20 mM | 0.2637 mL | 1.3183 mL | 2.6366 mL | 6.5915 mL | |
50 mM | 0.1055 mL | 0.5273 mL | 1.0546 mL | 2.6366 mL | |
100 mM | 0.0527 mL | 0.2637 mL | 0.5273 mL | 1.3183 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Octopamine hydrochloride 770-05-8 GPCR/G Protein Metabolism Neuroscience Dopamine Receptor Endogenous Metabolite Adrenergic Receptor neurotransmitter Inhibitor p-Octopamine hydrochlorid memory inhibit invertebrates learning 章鱼胺盐酸盐 (±)-p-Octopamine hydrochlorid neurohormone (+,-)-Octopamine HCl Octopamine Hydrochloride neuromodulator 章胺盐酸盐 Octopamine Beta Receptor Octopamine HCl inhibitor