首页 Metabolism NADPH Nucleocidin
Nucleocidin
编号 T16361     别名: 4'-Fluoro-5'-O-sulfamoyladenosine, NSC 521007
CAS 24751-69-7     分子式 C10H13FN6O6S     分子量 364.31
靶点: Antibacterial;
Nucleocidin is an antitrypanosomal antibiotic. Nucleocidin inhibiting the transfer of labeled amino acid from S-RNA to protein.
选择批次  
纯度 98.00%
规格 库存 单价 数量
100 mg 待询 待询
500 mg 待询 待询
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生物活性

产品描述

Nucleocidin is an antitrypanosomal antibiotic. Nucleocidin inhibiting the transfer of labeled amino acid from S-RNA to protein.

靶点活性

Antibacterial,

体外活性

Nucleocidin shows inhibition occurs at low concentrations, however, it is not possible to obtain complete inhibition at 10-3 M. Essentially complete inhibition is obtained at 10-3 M puromycin, and only at the lowest concentrations is any lag detectable. It seems that Nucleocidin exhibits the pattern typical of many antibiotics, i.e. it inhibits incorporation at a stage subsequent to the formation of aminoacyl-S-RNA. An appreciable lag occurs before any inhibition by Nucleocidin is detectable, and the length of this lag period varies inversely with the concentration of Nucleocidin. Similar results are obtained when Nucleocidin is added to the cell-free system from reticulocytes .

体内活性

化学信息

分子量

364.31

分子式

C10H13FN6O6S

CAS

24751-69-7

溶解度

( < 1 mg/ml refers to the product slightly soluble or insoluble )

储存条件

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

备注

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

配制溶液

1 mg 5 mg 10 mg
1 mM 2.745 ml 13.725 ml 27.449 ml
5 mM 0.549 ml 2.745 ml 5.49 ml
10 mM 0.274 ml 1.372 ml 2.745 ml
50 mM 0.055 ml 0.274 ml 0.549 ml
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