store at low temperture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nodosin 是一种二萜化合物,从Isodon trichocarpusKudo 和I. JaponicusHARA 中提取得到。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 1,162 | 现货 | ||
5 mg | ¥ 2,431 | 现货 | ||
10 mg | ¥ 3,598 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 2,669 | 现货 |
产品描述 | Nodosin has an anti-inflammatory function via inhibition of IL-2. Nodosin perfusion provides a potential protective effect by inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transplantation. |
体外活性 | In order to explore the anti-inflammatory effects of Nodosin from Isodon serra, a traditional Chinese herb medicine, mouse T lymphocytes were incubated with Nodosin.METHODS AND RESULTS: In the current study, Nodosin suppressed the overproduction of the T lymphocytes; moreover, the cell mitosis cycle was modulated by interfering with DNA replication in G1 stages via inhibition of IL-2 cytokine secretion at the mRNA level by Nodosin. Interestingly, Xylene-induced mouse tumescence model results suggested Nodosin depressed the murine ear-swelling extent and the level of IL-2 in the blood serum. |
分子量 | 362.42 |
分子式 | C20H26O6 |
CAS No. | 10391-09-0 |
store at low temperture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Nodosin 10391-09-0 Autophagy Immunology/Inflammation IL Receptor I. Japonicus Isodon trichocarpus inhibit Inhibitor diterpenoid inhibitor