store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nanchangmycin (Nanchangmycin A) 由 Streptomyces nanchangensis 产生的一种聚醚抗生素,抑制革兰氏阳性菌。它也是一种广谱抗病毒药物,有抗 Zika 病毒作用。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 583 | 待询 | ||
2 mg | ¥ 851 | 待询 | ||
5 mg | ¥ 1,560 | 待询 | ||
10 mg | ¥ 2,500 | 待询 | ||
25 mg | ¥ 4,190 | 待询 | ||
50 mg | 特惠询价 | 待询 | ||
1 mL * 10 mM (in DMSO) | ¥ 1,920 | 待询 |
Nanchangmycin 的其他形式现货产品:
产品描述 | Nanchangmycin (Nanchangmycin A), a polyether antibiotic, is similar to the structure of dianemycin. It is very potent against the broad spectrum of harmful nematodes and insects but not for mammals and plants. |
体外活性 | Nanchangmycin resists gram-positive bacteria. |
体内活性 | Nanchangmycin, a growth promoter in poultry, cures coccidiosis in chickens. Nanchangmycin, a bacterially-derived natural product, blocks ZIKV and DENV infection potently in diverse cell types. |
激酶实验 | Histone deacetylase activity:For PCI-34051 characterization, measurements are performed in a reaction volume of 100 μL using 96-well assay plates in a fluorescence plate reader. For each isozyme. The HDAC protein in reaction buffer (50 mM HEPES, 100 mM KCl, 0.001% Tween-20, 5% dimethyl sulfoxide, pH7.4, supplemented with bovine serum albumin at concentrations of 0-0.05%) is mixed with PCI-34051 at various concentrations and allowed to incubate for 15 min. Trypsin is added to a final concentration of 50 nM, and acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methyl coumarin is added to a final concentration of 25-100 μM to initiate the reaction. After a 30 min lag time, the fluorescence is measured over a 30 min time frame using an excitation wavelength of 335 nm and a detection wavelength of 460 nm. The increase in fluorescence with time is used as the measure of the reaction rate. |
细胞实验 | 5×10E3 U2OS cells were plated in 25ul media per well in 384-well plates and cultured for 24 hours. Add 50 nl of Nanchangmycin, which is 0.7uM dissolved in 0.2% DMSO, to each well incubating for 1 hour. |
别名 | Nanchangmycin A, 南昌霉素 |
分子量 | 889.1 |
分子式 | C47H77NaO14 |
CAS No. | 65101-87-3 |
store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 88.9 mg/mL (100 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 1.1247 mL | 5.6237 mL | 11.2473 mL | 28.1183 mL |
5 mM | 0.2249 mL | 1.1247 mL | 2.2495 mL | 5.6237 mL | |
10 mM | 0.1125 mL | 0.5624 mL | 1.1247 mL | 2.8118 mL | |
20 mM | 0.0562 mL | 0.2812 mL | 0.5624 mL | 1.4059 mL | |
50 mM | 0.0225 mL | 0.1125 mL | 0.2249 mL | 0.5624 mL | |
100 mM | 0.0112 mL | 0.0562 mL | 0.1125 mL | 0.2812 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Nanchangmycin 65101-87-3 Microbiology/Virology Antibacterial Antibiotic Inhibitor Nanchangmycin A 南昌霉素 inhibit Bacterial inhibitor