Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-Acetyl-L-aspartic acid (AC-ASP-OH) 是天冬氨酸的衍生物, 是由氨基酸天冬氨酸和乙酰辅酶 A 在神经元中合成的。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 mg | ¥ 258 | 现货 | ||
100 mg | ¥ 363 | 现货 | ||
200 mg | ¥ 545 | 待询 |
产品描述 | N-Acetyl-L-aspartic acid (AC-ASP-OH) is a derivative of aspartic acid. It is the second most concentrated molecule in the brain after the amino acid glutamate. It is synthesized in neurons from the amino acid aspartate and acetyl coenzyme A (acetyl CoA). The various functions served by N-Acetyl-L-aspartic acid (AC-ASP-OH) are still under investigation, but the primary proposed functions include (1) acting as a neuronal osmolyte that is involved in fluid balance in the brain, (2) serving as a source of acetate for lipid and myelin synthesis in oligodendrocytes (the glial cells that myelinate neuronal axons), (3) serving as a precursor for the synthesis of the important dipeptide neurotransmitter N-acetylaspartylglutamate (NAAG), and (4) playing a potential role in energy production from the amino acid glutamate in neuronal mitochondria. |
别名 | AC-ASP-OH, N-Acetylaspartic acid, N-乙酰-L-天门冬氨酸 |
分子量 | 175.14 |
分子式 | C6H9NO5 |
CAS No. | 997-55-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.33 mg/mL (19.03 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 5.7097 mL | 28.5486 mL | 57.0972 mL | 142.7429 mL |
5 mM | 1.1419 mL | 5.7097 mL | 11.4194 mL | 28.5486 mL | |
10 mM | 0.571 mL | 2.8549 mL | 5.7097 mL | 14.2743 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
N-Acetyl-L-aspartic acid 997-55-7 Metabolism Others Endogenous Metabolite N Acetyl L aspartic acid NAcetylLaspartic acid AC-ASP-OH Inhibitor N-Acetylaspartic acid N-乙酰-L-天门冬氨酸 inhibit inhibitor