首页 Apoptosis BCL Moringin
Moringin
编号 TN4583    
CAS 73255-40-0     分子式 C14H17NO5S     分子量 311.35
靶点: Bcl-2; Caspase; COX; gp120/CD4; GSK-3; IL Receptor; Nrf2; p53; PPAR; TNF-α; Wnt/β-catenin;
Moringin is a modulator of neuroinflammation via the β-catenin-PPARγ axis, it can activate Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis. Moringin is effective in inducing apoptosis through p53 and Bax activation and Bcl-2 inhibition, it demonstrates the antitumor efficacy in human malignant astrocytoma cells. The combination of cannabidiol and moringin has anti-inflammatory, antioxidative, and anti-apoptotic effects.
选择批次  
纯度 98.00%
规格 库存 单价 数量
1 mg 待询 2835.00
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生物活性

产品描述

Moringin is a modulator of neuroinflammation via the β-catenin-PPARγ axis, it can activate Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis. Moringin is effective in inducing apoptosis through p53 and Bax activation and Bcl-2 inhibition, it demonstrates the antitumor efficacy in human malignant astrocytoma cells. The combination of cannabidiol and moringin has anti-inflammatory, antioxidative, and anti-apoptotic effects.

靶点活性

Bcl-2,

Caspase,

COX,

gp120/CD4,

GSK-3,

IL Receptor,

Nrf2,

p53,

PPAR,

TNF-α,

Wnt/β-catenin,

体外活性

体内活性

化学信息

分子量

311.35

分子式

C14H17NO5S

CAS

73255-40-0

溶解度

( < 1 mg/ml refers to the product slightly soluble or insoluble )

储存条件

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

备注

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

配制溶液

1 mg 5 mg 10 mg
1 mM 3.212 ml 16.059 ml 32.118 ml
5 mM 0.642 ml 3.212 ml 6.424 ml
10 mM 0.321 ml 1.606 ml 3.212 ml
50 mM 0.064 ml 0.321 ml 0.642 ml
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