首页 Membrane transporter/Ion channel Calcium Channel Marmin
Marmin
编号 TN1913    
CAS 14957-38-1     分子式 C19H24O5     分子量 332.4
靶点: Calcium Channel; Histamine Receptor; Antifection;
Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and secondarily due to the prevention of the effects of endogenous acetylcholine and histamine.
选择批次  
纯度 98.00%
规格 库存 单价 数量
1 mg 待询 2273.00
大包装特惠,请咨询
大包装特惠,请咨询

生物活性

产品描述

Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and secondarily due to the prevention of the effects of endogenous acetylcholine and histamine.

靶点活性

Calcium Channel,

Histamine Receptor,

Antifection,

体外活性

In the study, we examined the effects of Marmin on the contraction of guinea pig-isolated trachea stimulated by several inducers, namely histamine, metacholine, compound 48/80. We also evaluated its action against contraction induced by extracellular or intracellular calcium ion. The possibility of Marmin to potentiate the relaxation effect of isoprenaline was also studied. Marmin added in the organ bath at 10 min prior to the agonist inhibited the contraction elicited by histamine and metacholine in a concentration-dependent manner. Moreover, Marmin antagonized the histamine-induced contraction in competitive manner. Marmin mildly potentiated the relaxation effect of isoprenaline. In the study, Marmin abrogated the contraction of tracheal smooth muscle induced by compound 48/80, an inducer of histamine release. Besides, Marmin successfully inhibited CaCl(2)-induced contraction in Ca(2+)-free Krebs solution. Marmin also inhibited two phases of contraction which were consecutively induced by metacholine and CaCl(2) in Ca(2+)-free Krebs solution[1]

体内活性

化学信息

分子量

332.4

分子式

C19H24O5

CAS

14957-38-1

溶解度

( < 1 mg/ml refers to the product slightly soluble or insoluble )

储存条件

store at -80°C

备注

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

配制溶液

1 mg 5 mg 10 mg
1 mM 3.008 ml 15.042 ml 30.084 ml
5 mM 0.602 ml 3.008 ml 6.017 ml
10 mM 0.301 ml 1.504 ml 3.008 ml
50 mM 0.06 ml 0.301 ml 0.602 ml
技术支持
在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-998-7375,或者邮箱 info@tsbiochem.com,直接联系到我们。我们会在24小时内尽快联系您。
订购方式
联系陶素
电话:400-821-2233
传真:021-34692979
邮箱:info@tsbiochem.com


  • 关注公众号
    - 超值特惠
    - 客户福利
    - 业界动态
    - 实用攻略
陶素的所有产品和服务仅用于科学研究,我们不为任何其他用途提供产品和服务(也不为任何个人提供产品和服务)。