首页 GPCR/G Protein Histamine Receptor Lavoltidine
Lavoltidine
编号 T15722     别名: Loxtidine, AH-234844
CAS 76956-02-0     分子式 C19H29N5O2     分子量 359.47
靶点: H2 Receptor;
Lavoltidine is an orally active and irreversible histamine H2-receptor antagonist. Lavoltidine strongly suppresses gastric acid secretion and also induces hypergastrinemia.
选择批次  
纯度 98.00%
规格 库存 单价 数量
100 mg 待询 待询
500 mg 待询 待询
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生物活性

产品描述

Lavoltidine is an orally active and irreversible histamine H2-receptor antagonist. Lavoltidine strongly suppresses gastric acid secretion and also induces hypergastrinemia.

靶点活性

H2 Receptor,

体外活性

体内活性

Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in H felis-infected INS-GAS mice. Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice. Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; 3 months) displays partial suppression of both gastric acid secretion and progression to neoplasia [1].

化学信息

分子量

359.47

分子式

C19H29N5O2

CAS

76956-02-0

溶解度

( < 1 mg/ml refers to the product slightly soluble or insoluble )

储存条件

store at -80°C

备注

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

配制溶液

1 mg 5 mg 10 mg
1 mM 2.782 ml 13.909 ml 27.819 ml
5 mM 0.556 ml 2.782 ml 5.564 ml
10 mM 0.278 ml 1.391 ml 2.782 ml
50 mM 0.056 ml 0.278 ml 0.556 ml
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