生物活性
|
产品描述 |
Lavoltidine is an orally active and irreversible histamine H2-receptor antagonist. Lavoltidine strongly suppresses gastric acid secretion and also induces hypergastrinemia. |
|
靶点活性 |
H2 Receptor, |
|
体外活性 |
|
|
体内活性 |
Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in H felis-infected INS-GAS mice. Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice. Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; 3 months) displays partial suppression of both gastric acid secretion and progression to neoplasia [1]. |
化学信息
|
分子量 |
359.47 |
|
分子式 |
C19H29N5O2 |
|
CAS |
76956-02-0 |
|
溶解度 |
（ < 1 mg/ml refers to the product slightly soluble or insoluble ) |
|
储存条件 |
store at -80°C |
|
备注 |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. |
配制溶液
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.782 ml | 13.909 ml | 27.819 ml |
| 5 mM | 0.556 ml | 2.782 ml | 5.564 ml |
| 10 mM | 0.278 ml | 1.391 ml | 2.782 ml |
| 50 mM | 0.056 ml | 0.278 ml | 0.556 ml |
产品操作手册
