首页Chromatin/EpigeneticEpigenetic Reader DomainJ147
J147
编号 T1993    
CAS 1146963-51-0     分子式 C18H17F3N2O2     分子量 350.34
靶点: BDNF;
J147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging that impacts many pathways implicated in the pathogenesis of diabetic neuropathy.
纯度:99.5%
规格 库存 单价 数量
10 mg 上海现货 722.00
25 mg 上海现货 1577.00
100 mg 上海现货 3779.00
1 mL * 10 mM (in DMSO) 上海现货 515.00
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生物活性

产品描述

J147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging that impacts many pathways implicated in the pathogenesis of diabetic neuropathy.

靶点活性

BDNF,

体外活性

体内活性

化学信息

分子量

350.34

分子式

C18H17F3N2O2

CAS

1146963-51-0

溶解度

DMSO: 35 mg/mL (100 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

储存条件

store at -80°C

备注

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

配制溶液

1 mg 5 mg 10 mg
1 mM 2.854 ml 14.272 ml 28.544 ml
5 mM 0.571 ml 2.854 ml 5.709 ml
10 mM 0.285 ml 1.427 ml 2.854 ml
50 mM 0.057 ml 0.285 ml 0.571 ml
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