Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Itaconic acid (methylene-butanedioicaci) 是聚合物,化学物质和燃料的合成前体。Itaconic acid 可由真菌合成。它也是巨噬细胞特异性代谢产物。它介导巨噬细胞代谢和腹膜肿瘤之间的串扰。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 224 | 现货 | ||
50 mg | ¥ 345 | 现货 | ||
100 mg | ¥ 496 | 现货 | ||
500 mg | ¥ 1,020 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 195 | 现货 |
产品描述 | Itaconic acid (methylene-butanedioicaci), also known as itaconate, belongs to the class of organic compounds known as branched fatty acids. These are fatty acids containing a branched chain. Itaconic acid exists as a solid, soluble (in water), and a weakly acidic compound (based on its pKa). Itaconic acid has been detected in multiple biofluids, such as sweat and urine. Within the cell, itaconic acid is primarily located in the mitochondria, cytoplasm and adiposome. Itaconic acid exists in all eukaryotes, ranging from yeast to humans. Adenosine triphosphate and itaconic acid can be converted into itaconyl-CoA; which is catalyzed by the enzyme succinyl-CoA ligase. Outside of the human body, itaconic acid can be found in a number of food items such as cowpea, butternut squash, brussel sprouts, and nopal. This makes itaconic acid a potential biomarker for the consumption of these food products. |
别名 | methylene-butanedioicaci, 衣康酸 |
分子量 | 130.1 |
分子式 | C5H6O4 |
CAS No. | 97-65-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (211.38 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 7.6864 mL | 38.432 mL | 76.864 mL | 192.1599 mL |
5 mM | 1.5373 mL | 7.6864 mL | 15.3728 mL | 38.432 mL | |
10 mM | 0.7686 mL | 3.8432 mL | 7.6864 mL | 19.216 mL | |
20 mM | 0.3843 mL | 1.9216 mL | 3.8432 mL | 9.608 mL | |
50 mM | 0.1537 mL | 0.7686 mL | 1.5373 mL | 3.8432 mL | |
100 mM | 0.0769 mL | 0.3843 mL | 0.7686 mL | 1.9216 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Itaconic acid 97-65-4 Metabolism Others Endogenous Metabolite inhibit Inhibitor methylene-butanedioicaci chemicals polymers 衣康酸 and fuels fungi macrophage inhibitor