Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Hexaconazole ((-)-Hexaconazol) 是一种广谱三唑类杀菌剂,通过抑制羊毛甾醇的细胞色素 P450 依赖性 14α-去甲基化来抑制麦角甾醇的生物合成,从而导致真菌细胞膜的破坏和细胞死亡。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 mg | ¥ 415 | 现货 | ||
500 mg | ¥ 591 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 457 | 现货 |
产品描述 | Hexaconazole ((-)-Hexaconazol) is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death. |
体外活性 | Hexaconazole is fungicidal against the powdery mildews B. graminis and S. cucurbitae on cucumber plants in a concentration-dependent manner and is curative against powdery mildew on barley plants when used at a concentration of 6.7 mg/L[1].It also inhibits growth of R. bataticola and S. rolfsii (ED50s = 6.35 and 1.27 mg/L, respectively)[2]. |
细胞实验 | The medium was poured into a set of two petriplates under aseptic conditions in a laminar flow hood.?When the medium in the plates was solidified, a mycelial disc of 0.5 cm diameter of freshly grown test fungi taken from periphery was inoculated upside down at the center of the plates.?These treated petri dishes were incubated at 28℃ until fungal growth in the control plates was almost complete.?Hexaconazole used as commercial fungicide and acetone served as control.?All the compounds were tested in triplicates.?The mycelia growth of fungi (mm) in both treated (T) and control (C) petri plates was measured diametrically in three different directions and growth inhibition (I) and corrected inhibition (IC) were calculated by using Abbott s formula[2] |
别名 | 己唑醇, (-)-Hexaconazol |
分子量 | 314.21 |
分子式 | C14H17Cl2N3O |
CAS No. | 79983-71-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (318.26 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 3.1826 mL | 15.9129 mL | 31.8258 mL | 79.5646 mL |
5 mM | 0.6365 mL | 3.1826 mL | 6.3652 mL | 15.9129 mL | |
10 mM | 0.3183 mL | 1.5913 mL | 3.1826 mL | 7.9565 mL | |
20 mM | 0.1591 mL | 0.7956 mL | 1.5913 mL | 3.9782 mL | |
50 mM | 0.0637 mL | 0.3183 mL | 0.6365 mL | 1.5913 mL | |
100 mM | 0.0318 mL | 0.1591 mL | 0.3183 mL | 0.7956 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Hexaconazole 79983-71-4 Immunology/Inflammation Metabolism Microbiology/Virology NF-Κb Reactive Oxygen Species Antifungal 己唑醇 inhibit Hexaconazol Inhibitor (-)-Hexaconazol Fungal inhibitor