首页 GPCR/G Protein Histamine Receptor Ganoderic acid C2
Ganoderic acid C2
编号 TN1661    
CAS 103773-62-2     分子式 C30H46O7     分子量 518.7
靶点: Histamine Receptor; Immunology & Inflammation related;
Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen.
选择批次  
纯度 98.00%
规格 库存 单价 数量
1 mg 待询 2095.00
5 mg 待询 6210.00
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生物活性

产品描述

Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen.

靶点活性

Histamine Receptor,

Immunology & Inflammation related,

体外活性

The metabolites and pharmacokinetics of Ganoderic acid C2 (GAC2), a bioactive triterpenoid in Ganoderma lucidum in rat plasma were investigated by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). Totally, ten minor phase I metabolites of GAC2 were characterized after oral administration of GAC2, on the basis of their mass fragmentation pathways or direct comparison with authentic compounds by high-performance liquid chromatography coupled with diode array detection and electrospray ion trap tandem mass spectrometry (HPLC-DAD-ESI-MS(n)), and liquid chromatography coupled with electrospray ionization hybrid ion trap and time-of-flight mass spectrometry (LC-ESI-IT-TOF/MS) methods. Moreover, a rapid and specific method for quantification of GAC2 in rat plasma after oral administration was developed by using a liquid-liquid extraction procedure and HPLC-ESI-MS/MS analysis.

体内活性

化学信息

分子量

518.7

分子式

C30H46O7

CAS

103773-62-2

溶解度

( < 1 mg/ml refers to the product slightly soluble or insoluble )

储存条件

store at -80°C

备注

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

配制溶液

1 mg 5 mg 10 mg
1 mM 1.928 ml 9.639 ml 19.279 ml
5 mM 0.386 ml 1.928 ml 3.856 ml
10 mM 0.193 ml 0.964 ml 1.928 ml
50 mM 0.039 ml 0.193 ml 0.386 ml
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