Fosamprenavir Calcium Salt

规格	价格/CNY		数量
1 mg	￥ 543	现货
2 mg	￥ 795	现货
5 mg	￥ 1,330	现货
10 mg	￥ 1,970	现货
25 mg	￥ 3,350	现货
50 mg	￥ 4,650	现货
100 mg	￥ 6,660	现货

规格

价格/CNY

货期

数量

1 mg

￥ 543

现货

2 mg

￥ 795

现货

5 mg

￥ 1,330

现货

10 mg

￥ 1,970

现货

25 mg

￥ 3,350

现货

50 mg

￥ 4,650

现货

100 mg

￥ 6,660

现货

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度

DMSO: 1.8 mg/mL (2.89 mM), Sonification and heating are recommended.

H2O: 0.25 mg/mL (0.40 mM), Sonification and heating are recommended.

溶液配制表

可选溶剂	浓度体积质量	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	1.6034 mL	8.0171 mL	16.0341 mL	40.0853 mL

产品描述	Fosamprenavir Calcium Salt (GW433908G) (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility. Fosamprenavir Calcium Salt has Anti-HIV infection.
体内活性	Oral gavage of DATS significantly retarded growth of PC-3 xenografts in athymic mice without causing weight loss. For instance, 20 days after starting therapy, the average tumor volume in control mice was approximately 3-fold higher compared with DATS-treated mice. Tumors from DATS-treated mice exhibited a markedly higher count of apoptotic bodies compared with control tumors. Consistent with the results in cultured PC-3 cells, the DATS-mediated suppression of PC-3 xenograft growth correlated with induction of proapoptotic proteins Bax and Bak. Although DATS treatment inhibited migration of cultured PC-3 cells in association with down-regulation of vascular endothelial growth factor receptor-2 protein, formation of new blood vessels was comparable in tumors of control and DATS-treated mice as judged by CD31 immunostaining[1].
动物实验	DATS was given orally (6 micromoL, thrice weekly) to male athymic mice s.c. implanted with PC-3 cells. Tumor sections from control and DATS-treated mice were examined for apoptotic bodies by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling assay. Protein levels of apoptosis and cell cycle regulating proteins in tumor tissues of control and DATS-treated mice were determined by immunoblotting. The effect of DATS treatment on in vivo angiogenesis was determined by immunohistochemical analysis of CD31 in tumors[1].

别名	福沙那伟钙, Diallyl Trisulfide, GW433908G
分子量	623.67
分子式	C25H34CaN3O9PS
CAS No.	226700-81-8

存储

溶解度

溶液配制表

计算器

输入分子式，点击计算，可计算出产品的分子量。

参考文献

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