首页 GPCR/G Protein Histamine Receptor Famotidine
Famotidine
编号 T1627     别名: MK-208
CAS 76824-35-6     分子式 C8H15N7O2S3     分子量 337.45
靶点: H2 receptor;
Famotidine is a propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli.
选择批次  
规格 库存 单价 数量
500 mg 上海现货 485.00
1 g 上海现货 755.00
1 mL * 10 mM (in DMSO) 上海现货 530.00
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生物活性

产品描述

Famotidine is a propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli.

靶点活性

H2 receptor,

体外活性

体内活性

化学信息

分子量

337.45

分子式

C8H15N7O2S3

CAS

76824-35-6

溶解度

DMSO: 62 mg/mL (183.7 mM)

Ethanol: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

储存条件

store at -80°C

备注

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

配制溶液

1 mg 5 mg 10 mg
1 mM 2.963 ml 14.817 ml 29.634 ml
5 mM 0.593 ml 2.963 ml 5.927 ml
10 mM 0.296 ml 1.482 ml 2.963 ml
50 mM 0.059 ml 0.296 ml 0.593 ml
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