FERULIC ACID METHYL ESTER

规格	价格/CNY		货期	数量
50 mg	￥ 99	现货
1 mL * 10 mM (in DMSO)	￥ 156	现货

规格

价格/CNY

货期

数量

50 mg

￥ 99

现货

1 mL * 10 mM (in DMSO)

￥ 156

现货

可选溶剂	浓度体积质量	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	4.8028 mL	24.0142 mL	48.0284 mL	120.0711 mL
5 mM	0.9606 mL	4.8028 mL	9.6057 mL	24.0142 mL
10 mM	0.4803 mL	2.4014 mL	4.8028 mL	12.0071 mL
20 mM	0.2401 mL	1.2007 mL	2.4014 mL	6.0036 mL
50 mM	0.0961 mL	0.4803 mL	0.9606 mL	2.4014 mL
100 mM	0.048 mL	0.2401 mL	0.4803 mL	1.2007 mL

可选溶剂

浓度体积质量

1 mg

5 mg

10 mg

25 mg

DMSO

1 mM

4.8028 mL

24.0142 mL

48.0284 mL

120.0711 mL

5 mM

0.9606 mL

4.8028 mL

9.6057 mL

24.0142 mL

10 mM

0.4803 mL

2.4014 mL

4.8028 mL

12.0071 mL

20 mM

0.2401 mL

1.2007 mL

2.4014 mL

6.0036 mL

50 mM

0.0961 mL

0.4803 mL

0.9606 mL

2.4014 mL

100 mM

0.048 mL

0.2401 mL

0.4803 mL

1.2007 mL

中药材名称	中药材拉丁名	性	味	归经
鸡血藤	Spatholobus suberectus Dunn	温	苦, 甘	肝, 肾

中药材名称

中药材拉丁名

性

味

归经

鸡血藤

Spatholobus suberectus Dunn

温

苦, 甘

肝, 肾

中成药名称	处方组成	主治疾病	中成药类型
参红祛瘀散结胶囊	人参,红花,黄氏,党参,当归,鸡血藤,延胡索(醋制),木香,枸杞子,龙眼肉,酸枣仁,白术,海藻,昆布,黄连,天花粉	口服。一次2-4粒，一日3次：儿童酌减或遵医曙。	扶正药
调经活血胶囊	木香,川芎,延胡索(醋制),当地,熟地黄,吴茱萸(甘草水制),泽兰,鸡血藤,菟丝子	口服。一次5片，一日3次。	理血药
丹黄祛瘀片	黄芪,丹参,党参,山药,土茯苓,当归,鸡血藤,芡实,鱼腥草,三棱,莪术,全蝎,败酱草,肉桂,白术,炮姜,土鳖虫,延胡索,川楝子,苦参	口服。每次 2～4 片，一日 2～3 次。	理气药
补肾固齿丸	熟地黄,紫河车,骨碎补(盐水炙),枸杞子,鸡血藤,野菊花,牡丹皮,郁金(醋炙),丹参(酒炙)	口服，一次4克，一日2次。	扶正药
丹珍头痛胶囊	高原丹参,夏枯草,熟地黄,珍珠母,鸡血藤,川芎,当归,白芍,菊花,蒺藜,钩藤,细辛	口服，每次3～4粒，一日3次；或遵医嘱。	治风药
丹郁骨康丸	丹参,郁金,三七,鸡血藤,牛膝,枸杞子	一日三次，每次一袋。	祛瘀药
安多霖胶囊	抗辐射植物提取物,鸡血藤	口服，一次4粒，一日3次。	扶正药
风湿祛痛胶囊	川黄柏,苍术,威灵仙,鸡血藤,蜂房,乌梢蛇,金钱白花蛇,蕲蛇,红花,土鳖虫,乳香,没药,全蝎,蜈蚣,地龙	口服，每次5粒每日3次，餐后30分钟口服，风湿性关节炎4周为一疗程。	活血通络药
参蓉健腰酒	人参,黄芪,黄精,玉竹,熟地黄,制何首乌,杜仲,枸杞子,肉苁蓉,菟丝子,狗肾(制),木香,陈皮,佛手,鸡血藤	口服，一次15-30ml，一日1-2次。	扶正药
定坤丹	人参,鹿茸,西红花,鸡血藤,白芍,熟地黄,当归,黄芩,香附,茺蔚子,川芎,延胡索	口服，一次半丸至1丸，一日2次。	扶正药

丹黄祛瘀胶囊	黄芪,丹参,党参,山药,土茯苓,当归,鸡血藤,芡实,鱼腥草,三棱,莪术,全蝎,败酱草,肉桂,白术,炮姜,土鳖虫,延胡索,川楝子,苦参	口服，一次2~4粒，一日2 ~3次。	理血药
妇科千金胶囊	穿心莲,单面针,当归,党参,功劳木,鸡血藤,金樱根,千斤拔	口服，一次2粒，一日3次，14天为一疗程。	清热药
补血宁神片	熟地黄,鸡血藤,首乌藤,金樱子	口服，一次5片，一日3次。	扶正药
参灵通络胶囊	黄氏,人参,灵芝,冬虫夏草,地龙,当归,鸡血藤,红花,牛膝,桃仁,赤芍,丹参,桂枝,没药	口服。一次4粒，一日3次，饭后30分钟后服用。	扶正药
妇科千金丸	穿心莲,单面针,当归,党参,功劳木,鸡血藤,金樱根,千斤拔	N/A	清热药
安康欣胶囊	半枝莲,山豆根,蒲公英,鱼腥草,夏枯草,石上柏,枸杞子,穿破石,人参,黄芪,鸡血藤,灵芝,黄精,白术,党参,淫羊藿,兔丝子,丹参	每日三次，每次4-6粒，饭后温开水送服。	安神药
虫草双参酒	冬虫夏草,人参,丹参,地黄,黄芪,淫羊藿,黄精,何首乌,枸杞子,山茱萸,鸡血藤	口服，一次15毫升，一日2次。疗程10天。	扶正药
安神养血口服液	钩藤,制首乌,鸡血藤	口服，一次30毫升，一日2次。	安神药
丹王颗粒	丹参,王不留行,土茯苓,三七,大蓟,玄参,蒲公英,桂枝,黄芩,皂角刺,没药,泽泻,鸡血藤,川牛膝	开水冲服，一次1袋，一日3次。	祛瘀药
风湿关节酒	乌梢蛇(酒炙),草乌(银花甘草炙),老鹳草,穿山龙,羌活,独活,铁丝威灵仙,香加皮,木瓜,苍术,防风,油松节,当归,川芎,桂枝,鸡血藤,牛膝,白芍,粉萆薢,佛手,人参,甘草,红曲	口服。一次15ml～20ml，一日2次。	祛风活络药

产品描述	FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activities that provide protection against inflammation and cancer. Ferulic acid methyl ester is a lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes.
体外活性	Ferulic acid methyl ester has less antioxidant capacity than ferulic acid in neuronal PC12 cells (IC50 = 74.7 μM for ferulic acid ethyl ester vs. 44.6 μM for ferulic acid, 2,2-diphenyl-1-picrylhydrazyl radical scavenging). Ferulic acid methyl ester, at 10-25 μg/ml, inhibits the release of pro-inflammatory cytokines, blocks the expression of COX-2, and reduces nitric oxide generation from LPS-stimulated macrophages.
激酶实验	DPPH radical scavenging activity of caffeic acid and ferulic acid derivatives was assessed as previously described withsome modifications. Briefly, the test compound was dissolved in dimethyl sulfoxide and 4 different concentrations weremixed with a methanolic solution of DPPH 100 mM in duplicate. After 30 min of incubation at room temperature in the dark, theabsorbance at 517 nm was measured by a spectrophotometer . The concentrations (in the range 1-100 μM) were carefully chosen for each compound in order to produce a suitable doseeresponse curve. The percent inhibition of the radical was calculated based on the absorbance of the mixture compared to the absorbance of DPPH solution alone.
细胞实验	Hydrogen peroxide (8.8 M solution) stored at 4 C was firstdiluted in PBS to prepare a 100 mM solution on the day of theexperiment. This was further diluted in growth medium to preparethe final working solution. PC12 cells were plated in collagencoated96-well microplates at a density of 5 105 cells/ml(100 μl per well). Blank wells contained only growth medium forbackground correction. After 48 h of incubation to allow for cellattachment, 20 μl of growth medium supplemented with differentconcentrations of HCAs were added in triplicate wells and preincubatedfor 1 h. Maximum concentration of DMSO in the wellswas kept below 0.2%. Afterwards, 20 μl of H2O2 solution was added.The concentration of H2O2 in the well was 75 μM. After anotherhour, the medium was replaced with fresh one and cells wereincubated overnight. In the end, the medium was replaced with30 μl of MTT 0.5 mg/ml dissolved in RPMI without phenol red.Formazan crystals were solubilised in 200 μl DMSO after 1.5 h ofincubation at 37 C.

别名	阿魏酸甲酯, Methyl ferulate, Methyl 4'-hydroxy-3'-methoxycinnamate
分子量	208.21
分子式	C11H12O4
CAS No.	2309-07-1

存储

溶解度

溶液配制表

中药材来源及性味归经

所属中成药

计算器

输入分子式，点击计算，可计算出产品的分子量。

参考文献

相关产品

相关化合物库

剂量换算

体内实验配液计算器

技术支持

Keywords