Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Epibrassinolide (BP55) 是一种广泛存在的植物生长激素,具有缓解植物重金属和农药胁迫潜力。它在各种癌细胞中是一种潜在的凋亡诱导剂。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 277 | 现货 | ||
5 mg | ¥ 595 | 现货 | ||
10 mg | ¥ 755 | 现货 | ||
25 mg | ¥ 932 | 现货 | ||
50 mg | ¥ 1,370 | 现货 | ||
100 mg | ¥ 1,980 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 663 | 现货 |
产品描述 | Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with a similar structure to mammalian steroids. |
体外活性 | Epibrassinolide(EBR) was shown as a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth[1].It has been shown to protect neuronal PC12 cells from 1-methyl-4-phenylpyridinium-induced oxidative stress and consequent apoptosis in dopaminergic neurons[2] |
细胞实验 | Cells were seeded at 1*10^4 density per well in 96-well plates and exposed to various concentrations of EBR for 24 and 48 h. 10 ul 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) dye (5 mg/ml) ?was added to each well and cells were kept at 37 C for 4 h. The resulting formazan crystals were solubilized in 200 ul DMSO.?The density of the solubilized formazan was read at 570 nm spectrophotometrically. |
别名 | 24-Epibrassinolide, B1105, 表油菜素内酯, BP55 |
分子量 | 480.68 |
分子式 | C28H48O6 |
CAS No. | 78821-43-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mg/mL (10.40 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.0804 mL | 10.4019 mL | 20.8039 mL | 52.0097 mL |
5 mM | 0.4161 mL | 2.0804 mL | 4.1608 mL | 10.4019 mL | |
10 mM | 0.208 mL | 1.0402 mL | 2.0804 mL | 5.201 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Epibrassinolide 78821-43-9 Apoptosis BP 55 inhibit Inhibitor B 1105 BP-55 24-Epibrassinolide B-1105 B1105 表油菜素内酯 BP55 inhibitor