Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Erb-196 is an estrogen receptor-receptor agonist with non-steroidal selectivity.
产品描述 | Erb-196 is an estrogen receptor-receptor agonist with non-steroidal selectivity. |
体内活性 | ERB-196 significantly reduces histopathologic evidence of injury to the gastrointestinal mucosal surface (0.7±0.1 vs. 2.3±0.2 for control;?p<0.05).?The mucosal mass of 10-cm segments of small bowel mucosa shows better preservation of mucosal mass than control treatment (63±20 [ERB-196] vs. 31±24 [control]), but this difference fails to reach statistical significance (p<0.06).?The administration of ERB-196 is highly effective in the prevention of lethality.?Consistent with the neutropenic rat model, ERB-196 significantly increases survival when compare with vehicle control. |
别名 | WAY-202196 |
分子量 | 279.27 |
分子式 | C17H10FNO2 |
CAS No. | 550997-55-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
ERB-196 550997-55-2 Endocrinology/Hormones Estrogen/progestogen Receptor WAY-202196 ERB 196 WAY202196 ERB196 WAY 202196 Inhibitor inhibitor inhibit