Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DOPEXAMINE 是一种多巴胺能激动剂。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 1,290 | 现货 | ||
2 mg | ¥ 1,950 | 现货 | ||
5 mg | ¥ 2,920 | 现货 | ||
10 mg | ¥ 4,320 | 现货 | ||
25 mg | ¥ 6,890 | 现货 | ||
50 mg | ¥ 9,330 | 现货 | ||
100 mg | ¥ 12,500 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 2,970 | 现货 |
产品描述 | Dopexamine is a dopaminergic agonist |
体内活性 | Dopexamine hydrochloride has interesting vasodilator properties, with marked intrinsic agonist activity at beta-2 adrenoreceptors and a lesser agonist activity at dopaminergic receptors (DA1 and DA2).?Dopexamine hydrochloride is responsible for an inhibition of neuronal re-uptake of catecholamines (uptake-1), producing an indirect stimulation of cardiac beta 1-receptors.?Dopexamine hydrochloride improves cardiac performance by a marked vasodilation and a mild inotropic activity.?The specific activity at dopaminergic receptors increases cerebral, myocardial, splanchnic and renal blood flows.?These haemodynamic effects are associated with an increase in diuresis and natriuresis.?These benefits are achieved without side effects such as an increased myocardial oxygen consumption, although induced tachycardia may be responsible for chest pain/anginae pain in patients with ischaemic heart disease[1]. |
分子量 | 356.5 |
分子式 | C22H32N2O2 |
CAS No. | 86197-47-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (154.28 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.805 mL | 14.0252 mL | 28.0505 mL | 70.1262 mL |
5 mM | 0.561 mL | 2.805 mL | 5.6101 mL | 14.0252 mL | |
10 mM | 0.2805 mL | 1.4025 mL | 2.805 mL | 7.0126 mL | |
20 mM | 0.1403 mL | 0.7013 mL | 1.4025 mL | 3.5063 mL | |
50 mM | 0.0561 mL | 0.2805 mL | 0.561 mL | 1.4025 mL | |
100 mM | 0.0281 mL | 0.1403 mL | 0.2805 mL | 0.7013 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
DOPEXAMINE 86197-47-9 GPCR/G Protein Neuroscience Dopamine Receptor Inhibitor inhibitor inhibit