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Chromium picolinate

Chromium picolinate

产品编号 T4575   CAS 14639-25-9

Chromium picolinate 具有降低胰岛素抵抗的作用,对 2 型糖尿病具有潜在的研究价值。

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Chromium picolinate Chemical Structure
Chromium picolinate, CAS 14639-25-9
规格 价格/CNY 货期 数量
100 mg ¥ 415 现货
1 mL * 10 mM (in DMSO) ¥ 373 现货
产品目录号及名称: Chromium picolinate (T4575)
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生物活性
化学信息
存储 & 溶解度
参考文献
产品描述 Chromium picolinate causes DNA damage and mutation. It is an activator of p38.
体内活性 Acrivastine (usually 8mg three times daily) is an effective and well-tolerated antihistamine in the treatment of chronic urticaria and allergic rhinitis. Acrivastine causes less drowsiness than clemastine, the incidence of adverse effects being indistinguishable from that with placebo or terfenadine. In the treatment of dermatoses in which histamine has a pathogenetic role, the efficacy of acrivastine is superior to that of placebo and similar to that of usual dosages of clemastine, hydroxyzine, chlorpheniramine, cyproheptadine or terfenadine [1]. Both 4 mg and 8 mg acrivastine alleviate the symptoms of seasonal allergic rhinitis with significant improvements in the symptom scores for sneezing, running nose and the calculated overall score. In addition, 8 mg acrivastine reduces the symptom scores for watery eyes and itchy throat. Acrivastine is both well tolerated and effective in the treatment of seasonal allergic rhinitis [2].
分子量 418.3
分子式 C18H12CrN3O6
CAS No. 14639-25-9

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度

DMSO: 4.18 mg/mL (10 mM), Sonification is recommended

溶液配制表

可选溶剂 浓度 体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3906 mL 11.9531 mL 23.9063 mL 59.7657 mL
5 mM 0.4781 mL 2.3906 mL 4.7813 mL 11.9531 mL
10 mM 0.2391 mL 1.1953 mL 2.3906 mL 5.9766 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器
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输入分子式,点击计算,可计算出产品的分子量。

参考文献

1. Diaz M L, et al. Chromium picolinate and conjugated linoleic acid do not synergistically influence diet- and exercise-induced changes in body composition and health indexes in overweight women[J]. Journal of Nutritional Biochemistry, 2008, 19(1):61-68. 2. Hynes A M J, Rouvinen-Watt K. Monitoring blood glucose levels in female mink during the reproductive cycle: 1. Prevention of hyperglycemia during the nursing period[J]. Canadian Journal of Veterinary Research, 2007, 71(4):241. 3. He C, Sun S, Zhang Y, et al. The role of irreversible electroporation in promoting M1 macrophage polarization via regulating the HMGB1-RAGE-MAPK axis in pancreatic cancer[J]. OncoImmunology. 2021, 10(1): 1897295.

文献引用

1. He C, Sun S, Zhang Y, et al. The role of irreversible electroporation in promoting M1 macrophage polarization via regulating the HMGB1-RAGE-MAPK axis in pancreatic cancer. OncoImmunology. 2021 Mar 11;10(1):1897295. doi: 10.1080/2162402X.2021.1897295. 2. Zheng H, Hu Y, Shao M, et al.Chromium Picolinate Protects against Testicular Damage in STZ-Induced Diabetic Rats via Anti-Inflammation, Anti-Oxidation, Inhibiting Apoptosis, and Regulating the TGF-β1/Smad Pathway.Molecules.2023, 28(22): 7669.
Esculin sesquihydrate Doramapimod Lucideric acid A Agrimonolide UM-164 Physalin A Talmapimod Isofraxidin

相关化合物库

该产品包含在如下化合物库中:
抗癌上市药物库 抗癌药物库 抗癌临床化合物库 NO PAINS 化合物库 临床期小分子药物库 成骨分子库 FDA 上市激酶抑制剂库 药物功能重定位化合物库 抗代谢疾病化合物库 FDA上市及药典收录分子库

剂量换算

对于不同动物的给药剂量换算,您也可以参考 更多...

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。

母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。

体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。

第一步:请输入动物实验的基本信息
剂量
mg/kg
每只动物体重
g
给药体积
μL
动物数量
第二步:请输入动物体内配方组成,不同的产品配方组成不同,如有配方需求,可先联系我们提供正确的体内配方。
% DMSO
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% Tween 80
% ddH2O
计算 重置

技术支持

您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。

Keywords

Chromium picolinate 14639-25-9 DNA Damage/DNA Repair MAPK DNA p38 MAPK Inhibitor inhibit Chromium (III) picolinate Cr(Pic)3 inhibitor

 

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