首页 GPCR/G Protein Histamine Receptor Chlorcyclizine hydrochloride
Chlorcyclizine hydrochloride
编号 T10794    
CAS 14362-31-3     分子式 C18H22Cl2N2     分子量 337.29
靶点: Histamine H1;
Chlorcyclizine hydrochloride is an antagonist of histamine H1.
选择批次  
纯度 98.00%
规格 库存 单价 数量
100 mg 待询 630.00
200 mg 待询 970.00
500 mg 待询 1990.00
1 g 待询 待询
1 mL * 10 mM (in DMSO) 待询 690.00
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生物活性

产品描述

Chlorcyclizine hydrochloride is an antagonist of histamine H1.

靶点活性

Histamine H1,

体外活性

体内活性

Pregnant rats administered 30, 60, and 90mg/kg Chlorcyclizine during the sensitive period for palate development survived until scheduled sacrifice on Gestation Days (GDs) 17 or 21. The rats administered 60 or 90mg/kg Chlorcyclizine have transient adverse clinical signs and a concomitant body weight loss of 7% and 11%, respectively, over the dosing interval. Rats administered 30mg/kg Chlorcyclizine do not exhibit any adverse clinical signs, but do not gain weight over the dosing interval as would be expected during pregnancy.

化学信息

分子量

337.29

分子式

C18H22Cl2N2

CAS

14362-31-3

溶解度

DMSO: 77.5 mg/mL (229.77 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

储存条件

store at -80°C

备注

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

配制溶液

1 mg 5 mg 10 mg
1 mM 2.965 ml 14.824 ml 29.648 ml
5 mM 0.593 ml 2.965 ml 5.93 ml
10 mM 0.296 ml 1.482 ml 2.965 ml
50 mM 0.059 ml 0.296 ml 0.593 ml
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