Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chelidonine hydrochloride 是 Chelidonium majus 的生物碱之一,具有广泛的药理活性。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 453 | 现货 | ||
5 mg | ¥ 1,080 | 现货 | ||
10 mg | ¥ 1,600 | 现货 | ||
25 mg | ¥ 2,690 | 现货 | ||
50 mg | ¥ 3,930 | 待询 |
产品描述 | Chelidonine hydrochloride is one of the alkaloids of Chelidonium majus, which has broad pharmacological activities |
体外活性 | Chelidonine significantly suppressed LPS-induced the production of NO and PGE2, as well as iNOS and COX-2 mRNA and protein expression.?In addition, pro-inflammatory cytokines induced by LPS, such as TNFα and IL-6 were also attenuated by chelidonine.?What's more, LPS-induced activation and degradation of IκBα followed by translocation of the p65 from the cytoplasm to the nucleus were attenuated by chelidonine.?Furthermore, chelidonine even significantly inhibited TLR4 expression induced by LPS[1]. |
分子量 | 353.37 |
分子式 | C20H19NO5 |
CAS No. | 4312-31-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: <10mM
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.8299 mL | 14.1495 mL | 28.299 mL | 70.7474 mL |
5 mM | 0.566 mL | 2.8299 mL | 5.6598 mL | 14.1495 mL | |
10 mM | 0.283 mL | 1.4149 mL | 2.8299 mL | 7.0747 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Chelidonine hydrochloride 4312-31-6 Others Chelidonine Hydrochloride Inhibitor inhibitor inhibit