Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cerebroside B1b has antiulcerogenic activity.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 mg | ¥ 3,230 | 待询 | ||
1 mL * 10 mM (in DMSO) | ¥ 4,940 | 待询 |
产品描述 | Cerebroside B1b has antiulcerogenic activity. |
体外活性 | Here, fusaruside is clarified biosynthetically, and its efficacy-related 10,11-double bond can be generated under the regioselective catalysis of an unprecedented α?10(E)-sphingolipid desaturase (α?10(E)-SD). α?10(E)-SD shares 17.7% amino acid sequence similarity with a C9-unmethylated α?10-sphingolipid desaturase derived from a marine diatom, and 55.7% with α?8(E)-SD from Fusarium graminearum. Heterologous expression of α?10(E)-SD in Pichia pastoris has been established to facilitate a reliable generation of 1 through the α?10(E)-SD catalyzed desaturation of Cerebroside B (2), an abundant fungal sphingolipid. Site directed mutageneses show that the conserved histidines of α?10(E)-SD are essential for the 10,11-desaturation catalysis, which is also preconditioned by the C9-methylation of the substrate. Moreover, α?10(E)-SD confers improved survival and faster growth to fungal strains at low temperature and high salinity, in parallel with to higher contents of 1 in the mycelia. |
分子量 | 728.065 |
分子式 | C41H77NO9 |
CAS No. | 88642-46-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Cerebroside B 88642-46-0 Microbiology/Virology Antifection Inhibitor inhibitor inhibit