Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Butoconazole nitrate (RS 35887) 是一种咪唑类抗真菌药物,可治疗由白色念珠菌引起的阴道感染。它可通过抑制类固醇合成起到抗菌作用。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 mg | ¥ 289 | 现货 | ||
100 mg | ¥ 413 | 现货 | ||
200 mg | ¥ 583 | 现货 | ||
500 mg | ¥ 963 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 455 | 现货 |
产品描述 | Butoconazole Nitrate is the nitrate salt form of butoconazole, a synthetic imidazole derivative with fungistatic properties. Butoconazole nitrate (RS 35887) interferes with steroid biosynthesis by inhibiting the conversion of lanosterol to ergosterol, thereby changing the fungal cell membrane lipid composition. This alters cell permeability and leads to growth inhibition. Butoconazole nitrate is active against many dermatophytes and yeasts. It also contains antibacterial effects against some gram-positive organisms. |
体内活性 | Dexpanthenol has positive effects on protection of cerebral tissue after ischaemia reperfusion[1]. Topical application of dexpanthenol is widely used in clinical practice for the improvement of wound healing. Upregulation of IL-6, IL-1, CYP1B1, CXCL1, CCL18 and KAP 4-2 gene expression and downregulation of psorasin mRNA and protein expression are identified in samples treated topically with dexpanthenol[2]. |
别名 | RS 35887, 硝酸布康唑 |
分子量 | 474.79 |
分子式 | C19H18Cl3N3O3S |
CAS No. | 64872-77-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 88 mg/mL (185.3 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.1062 mL | 10.531 mL | 21.0619 mL | 52.6549 mL |
5 mM | 0.4212 mL | 2.1062 mL | 4.2124 mL | 10.531 mL | |
10 mM | 0.2106 mL | 1.0531 mL | 2.1062 mL | 5.2655 mL | |
20 mM | 0.1053 mL | 0.5265 mL | 1.0531 mL | 2.6327 mL | |
50 mM | 0.0421 mL | 0.2106 mL | 0.4212 mL | 1.0531 mL | |
100 mM | 0.0211 mL | 0.1053 mL | 0.2106 mL | 0.5265 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Butoconazole nitrate 64872-77-1 Endocrinology/Hormones Microbiology/Virology Estrogen/progestogen Receptor Antifungal Butoconazole Nitrate RS 35887 RS35887 Inhibitor Butoconazole Fungal RS-35887 inhibit 硝酸布康唑 inhibitor