Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bretylium tosylate 是交感神经和肾上腺素神经的阻断剂,是血管收缩的神经递质突触前释放的抑制剂。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
2 mg | ¥ 298 | 现货 | ||
5 mg | ¥ 554 | 现货 | ||
10 mg | ¥ 814 | 现货 | ||
50 mg | ¥ 1,298 | 现货 | ||
100 mg | ¥ 1,614 | 现货 | ||
200 mg | ¥ 2,398 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 598 | 现货 |
产品描述 | Bretylium tosylate is an inhibitor of the presynaptic release of vasoconstrictor neurotransmitters, a available antiarrhythmic drug for ventricular arrhythmias. |
体内活性 | Nine patients who had recurrent ventricular fibrillation following acute myocardial infarction or angina were given bretylium tosylate in a dose of 5 mg./kg. intramuscularly every eight hours after other measures had proved ineffective. Provided the patients were not in shock or in heart failure, there was a considerable reduction in the episodes of ventricular fibrillation.A second group of nine patients who developed recurrent ventricular fibrillation following open heart surgery were given bretylium intravenously, which controlled the arrhythmia in every instance.Bretylium did not completely abolish ventricular premature beats but the latter did not initiate ventricular fibrillation even when they occurred on the T wave[1]. |
别名 | 溴苄乙胺, 托西溴苄铵 |
分子量 | 414.36 |
分子式 | C18H24BrNO3S |
CAS No. | 61-75-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (72.40 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.4134 mL | 12.0668 mL | 24.1336 mL | 60.334 mL |
5 mM | 0.4827 mL | 2.4134 mL | 4.8267 mL | 12.0668 mL | |
10 mM | 0.2413 mL | 1.2067 mL | 2.4134 mL | 6.0334 mL | |
20 mM | 0.1207 mL | 0.6033 mL | 1.2067 mL | 3.0167 mL | |
50 mM | 0.0483 mL | 0.2413 mL | 0.4827 mL | 1.2067 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Bretylium tosylate 61-75-6 Others inhibit 溴苄乙胺 Bretylium Tosylate Inhibitor Bretylium 托西溴苄铵 inhibitor