Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Baicalin methyl ester 是黄芩苷根的一种成分。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 418 | 现货 | ||
5 mg | ¥ 970 | 现货 | ||
10 mg | ¥ 1,484 | 现货 | ||
25 mg | ¥ 2,490 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 996 | 现货 |
产品描述 | Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT). |
体外活性 | One hundred-ninety flavonoids and 75 alkaloids were studied for their inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT) by using (rA) n-p(dT) <12-18> or (rC) n-p(dG) <12-18> as a template-primer. Of the flavonoids tested, 6-hydroxyluteolin (50), pedalitin (52), 6-hydroxykaempferol (109) and quercetagetin (129), were the most potent inhibitors with IC50?:10 μM. Five other flavonoids, baicalein (19), Baicalin methyl ester (23), scutellarein (33), myricetin (126) and gossypetin (130), gave IC50 between 35 and 200 μM. The kinetic studies on 50, 126 and 130 gave the inhibitory constants ki of 10, 94 and 90 μM, respectively, with respect to the substrate and 5, 200 and 100 μM, respectively, with respect to the template-primer. Structurally different alkaloids such as isoquinoline, indol, steroidal, quinolizidine, pyrrolizidine, pyridine and imidazole alkaloids were also investigated for the activity and berberine type alkaloids were shown to have a strong inhibitory activity. |
分子量 | 460.39 |
分子式 | C22H20O11 |
CAS No. | 82475-03-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (97.74 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.1721 mL | 10.8604 mL | 21.7207 mL | 54.3018 mL |
5 mM | 0.4344 mL | 2.1721 mL | 4.3441 mL | 10.8604 mL | |
10 mM | 0.2172 mL | 1.086 mL | 2.1721 mL | 5.4302 mL | |
20 mM | 0.1086 mL | 0.543 mL | 1.086 mL | 2.7151 mL | |
50 mM | 0.0434 mL | 0.2172 mL | 0.4344 mL | 1.086 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Baicalin methyl ester 82475-03-4 Microbiology/Virology Anti-infection Inhibitor inhibit inhibitor