BMY-25271
编号 T10575
CAS 78441-82-4
分子式
C12H19N5O2S2
分子量
329.44
靶点：
Histamine H2 receptor;
BMY-25271 is an antagonist of histamine H2 receptor.
生物活性
|
产品描述 |
BMY-25271 is an antagonist of histamine H2 receptor. |
|
靶点活性 |
Histamine H2 receptor, |
|
体外活性 |
|
|
体内活性 |
The dose-response curves are parallel and oral ED50 values derived from probit analysis are 0.093, 0.97, and 6.9 mg/kg for BMY-25271, ranitidine, and cimetidine, respectively. BMY-25271 is about 10 and 74 times more potent than ranitidine and cimetidine, respectively. |
化学信息
|
分子量 |
329.44 |
|
分子式 |
C12H19N5O2S2 |
|
CAS |
78441-82-4 |
|
溶解度 |
（ < 1 mg/ml refers to the product slightly soluble or insoluble ) |
|
储存条件 |
store at -80°C |
|
备注 |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. |
配制溶液
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.035 ml | 15.177 ml | 30.355 ml |
| 5 mM | 0.607 ml | 3.035 ml | 6.071 ml |
| 10 mM | 0.304 ml | 1.518 ml | 3.035 ml |
| 50 mM | 0.061 ml | 0.304 ml | 0.607 ml |
产品操作手册
