Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Azaperone (Fluoperidol) 是多巴胺拮抗剂,具有一些抗组胺和抗胆碱特性,具有止吐活性。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 mg | ¥ 139 | 现货 | ||
10 mg | ¥ 188 | 现货 | ||
25 mg | ¥ 297 | 现货 | ||
50 mg | ¥ 421 | 现货 | ||
100 mg | ¥ 588 | 现货 | ||
200 mg | ¥ 858 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 128 | 现货 |
产品描述 | Azaperone (Fluoperidol) is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine. |
体内活性 | Azaperone eliminates fighting only for a few hours after it is administered, after which the behaviour of pigs treated with it is not different from that of non-tranquillized mixed pigs. [1] Azaperone (2.2 mg/kg i.m.) reduces total fighting from 309.8 min for saline to 189.6 min in pigs. [2] Azaperone (103.1 mg) combined with Butorphanol (69.3 mg) produces adequate muscle relaxation and apparently adequate analgesia for minor surgical interferences, including abdominal laparoscopy, in a white rhinoceros with chronic renal disease. [3] Azaperone combined with Butorphanol and Medetomidine (BAM: 0.43 mg/kg Butorphanol, 0.36 mg/kg Azaperone, 0.14 mg/kg Medetomidine) results in a predictable onset of sedation, with a mean induction time to lateral recumbency of 9.8 min, in white-tailed deer. Azaperone combined with Butorphanol and Medetomidine (BAM: 0.43 mg/kg Butorphanol, 0.36 mg/kg Azaperone, 0.14 mg/kg Medetomidine) results in decreased heart rate and increased arterial partial pressure of carbon dioxide (PaCO2) in white-tailed deer. [4] Azaperone (1.0 mg/kg) combined with Ketamine (15 mg/kg) and Climazolam (1.5 mg/kg) results in a significantly higher castration score, when administrated intranasally (IN) compared with intramuscularly (IM) in piglets, there is an association between castration score and room temperature in the IN group. Azaperone (1.0 mg/kg) combined with Ketamine (15 mg/kg) and Climazolam (1.5 mg/kg) results in higher heart rate in the IN group of piglets. Azaperone (1.0 mg/kg) combined with Ketamine (15 mg/kg) and Climazolam (1.5 mg/kg) results in higher respiratory rate and walking significantly faster in the IM group of piglets. [5] |
别名 | R-1929, Fluoperidol, 阿扎哌隆, Stresnil, NSC 170976, Suicalm |
分子量 | 327.4 |
分子式 | C19H22FN3O |
CAS No. | 1649-18-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (183.3 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 32 mg/mL (97.7 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO / Ethanol | 1 mM | 3.0544 mL | 15.2718 mL | 30.5437 mL | 76.3592 mL |
5 mM | 0.6109 mL | 3.0544 mL | 6.1087 mL | 15.2718 mL | |
10 mM | 0.3054 mL | 1.5272 mL | 3.0544 mL | 7.6359 mL | |
20 mM | 0.1527 mL | 0.7636 mL | 1.5272 mL | 3.818 mL | |
50 mM | 0.0611 mL | 0.3054 mL | 0.6109 mL | 1.5272 mL | |
DMSO | 100 mM | 0.0305 mL | 0.1527 mL | 0.3054 mL | 0.7636 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Azaperone 1649-18-9 GPCR/G Protein Neuroscience Others Dopamine Receptor R-1929 NSC170976 Fluoperidol inhibit Inhibitor 阿扎哌隆 R 1929 Stresnil NSC-170976 R1929 NSC 170976 Suicalm inhibitor