Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Arjunolic acid 是分离自蓝莓的皂苷,具有抗氧化、抗菌和抗炎症等多种生物活性,在保护细胞和组织免受活性氧的有害作用中发挥重要作用。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 1,670 | 现货 | ||
5 mg | ¥ 4,230 | 现货 | ||
10 mg | ¥ 5,900 | 现货 | ||
25 mg | ¥ 9,170 | 现货 | ||
50 mg | ¥ 12,300 | 现货 | ||
100 mg | ¥ 16,600 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 4,690 | 现货 |
产品描述 | Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the development of innovative multi-functional medicines for Alzheimer desease treatment. |
体外活性 | This review highlights the beneficial role of Arjunolic acid, a naturally occurring chiral triterpenoid saponin, in various organ pathophysiology and the underlying mechanism of its protective action. Studies on the biochemistry and pharmacology suggest the potential use of Arjunolic acid as a novel promising therapeutic strategy. WHAT THE READERS WILL GAIN: The multifunctional therapeutic application of Arjunolic acid has already been documented by its various biological functions including antioxidant, anti-fungal, anti-bacterial, anticholinesterase, antitumor, antiasthmatic, wound healing and insect growth inhibitor activities. The scientific basis behind its therapeutic application as a cardioprotective agent in traditional medicine is justified by its ability to prevent myocardial necrosis and apoptosis, platelet aggregation, coagulation and lowering of blood pressure, heart rate, as well as cholesterol levels. Its antioxidant property coupled with metal chelating property (by its two hydroxyl groups) protects different organs from metal and drug-induced organ pathophysiology. Arjunolic acid also plays a beneficial role in the pathogenesis of diabetes and its associated complications. The mechanism of cytoprotection of Arjunolic acid, at least in part, results from the detoxification of reactive oxygen species (ROS) produced in the respective pathophysiology. In addition to its other biological functions, it also possesses vibrant insecticidal properties and it has the potential to be used as a structural molecular framework for the design of molecular receptors in the general area of supramolecular chemistry and nanochemistry. Esters of Arjunolic acid function as organogelators which has wide application in designing thermochromic switches and sensor devices. Arjunolic acid derived crown ether is an attractive candidate for the design of molecular receptors, biomimetics and supramolecular systems capable of performing some biological functions[1] |
分子量 | 488.7 |
分子式 | C30H48O5 |
CAS No. | 465-00-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (204.62 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.0462 mL | 10.2312 mL | 20.4625 mL | 51.1561 mL |
5 mM | 0.4092 mL | 2.0462 mL | 4.0925 mL | 10.2312 mL | |
10 mM | 0.2046 mL | 1.0231 mL | 2.0462 mL | 5.1156 mL | |
20 mM | 0.1023 mL | 0.5116 mL | 1.0231 mL | 2.5578 mL | |
50 mM | 0.0409 mL | 0.2046 mL | 0.4092 mL | 1.0231 mL | |
100 mM | 0.0205 mL | 0.1023 mL | 0.2046 mL | 0.5116 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Arjunolic acid 465-00-9 Apoptosis Immunology/Inflammation MAPK Metabolism Neuroscience NF-Κb IL Receptor TNF Reactive Oxygen Species JNK AChE hepatocyte injury hyperglycemia Inhibitor type 1 diabetes antimicrobial antioxidant Antidiabetic antibacterial inhibit Symplocos lancifolia reactive oxygen inhibitor