| 规格 | 库存 | 单价 | 数量 |
|---|---|---|---|
| 50 mg | 上海现货 | 410.00 |
|
| 100 mg | 上海现货 | 574.00 |
|
| 1 mL * 10 mM (in DMSO) | 上海现货 | 434.00 |
|
生物活性
|
产品描述 |
Antazoline hydrochloride, a first-generation antihistamine, can bind to the histamine H1 receptor and block the action of endogenous histamine. |
|
靶点活性 |
H1 receptor, |
|
体外活性 |
30 μM Antazoline即可降低由NMDA介导的神经毒性,还可阻断NMDA电流依赖的电压和快速可逆作用,电压在 -60 mV下抑制率为85±3%。 |
|
体内活性 |
在帧内梨形毛果芸香碱诱导的持续癫痫状态模型中,Antazoline可用来保护体内的神经. |
化学信息
|
分子量 |
301.82 |
|
分子式 |
C17H19N3·HCl |
|
CAS |
2508-72-7 |
|
溶解度 |
Ethanol: 4 mg/mL (13.25 mM) Water: 14 mg/mL (46.38 mM) DMSO: 40 mg/mL (132.53 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble ) |
|
储存条件 |
store at -80°C |
|
备注 |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. |
配制溶液
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.313 ml | 16.566 ml | 33.132 ml |
| 5 mM | 0.663 ml | 3.313 ml | 6.626 ml |
| 10 mM | 0.331 ml | 1.657 ml | 3.313 ml |
| 50 mM | 0.066 ml | 0.331 ml | 0.663 ml |
产品操作手册
