Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Acrivastine (Acrivastin) 是一种短效组胺 1 受体拮抗剂,可用于研究过敏性鼻炎。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 mg | ¥ 272 | 现货 | ||
10 mg | ¥ 455 | 现货 | ||
25 mg | ¥ 863 | 现货 | ||
50 mg | ¥ 1,270 | 现货 | ||
100 mg | ¥ 1,880 | 现货 | ||
500 mg | ¥ 4,670 | 现货 | ||
1 g | ¥ 6,590 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 283 | 现货 |
产品描述 | Acrivastine (Acrivastin) is a short-acting histamine 1 receptor antagonist. |
体内活性 | Acrivastine (usually 8mg three times daily) is an effective and well-tolerated antihistamine in the treatment of chronic urticaria and allergic rhinitis. Acrivastine causes less drowsiness than clemastine, the incidence of adverse effects being indistinguishable from that with placebo or terfenadine. In the treatment of dermatoses in which histamine has a pathogenetic role, the efficacy of acrivastine is superior to that of placebo and similar to that of usual dosages of clemastine, hydroxyzine, chlorpheniramine, cyproheptadine or terfenadine [1]. Both 4 mg and 8 mg acrivastine alleviate the symptoms of seasonal allergic rhinitis with significant improvements in the symptom scores for sneezing, running nose and the calculated overall score. In addition, 8 mg acrivastine reduces the symptom scores for watery eyes and itchy throat. Acrivastine is both well tolerated and effective in the treatment of seasonal allergic rhinitis [2]. |
别名 | Acrivastin, 阿伐斯汀, BW825C, Semprex |
分子量 | 348.44 |
分子式 | C22H24N2O2 |
CAS No. | 87848-99-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mg/mL (14.35 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.8699 mL | 14.3497 mL | 28.6993 mL | 71.7484 mL |
5 mM | 0.574 mL | 2.8699 mL | 5.7399 mL | 14.3497 mL | |
10 mM | 0.287 mL | 1.435 mL | 2.8699 mL | 7.1748 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Acrivastine 87848-99-5 GPCR/G Protein Immunology/Inflammation Neuroscience Histamine Receptor Acrivastin 阿伐斯汀 inhibit BW825C Semprex Inhibitor inhibitor