Powder: -20°C for 3 years | In solvent: -80°C for 1 year
7-Ethoxyrosmanol has cytotoxic and antimicrobial activities.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
20 mg | ¥ 3,330 | 待询 | ||
1 mL * 10 mM (in DMSO) | ¥ 1,580 | 待询 |
产品描述 | 7-Ethoxyrosmanol has cytotoxic and antimicrobial activities. |
体外活性 | The cytotoxic activity of compounds 1 and 2 was evaluated against a panel of three cancer cell lines (MCF7, HeLa and HT29) using curcumin as positive control. Carnosol (2) showed cytotoxic activity against all three cell lines having a similar response as the positive control with an IC50 approximately of 15-20 μg/mL in each case. On the other hand, 7-Ethoxyrosmanol (1) showed lower activity than carnosol, with an IC50 approx. of 20-30 μg/mL for the three cancer cell lines. This is the first report on cytotoxic activity against MCF7, HeLa and HT29 cancer cell lines and the antimicrobial activity of compound 1, and the first report on cytotoxic activity against HeLa of compound 2. In addition, the main volatile components of the essential oil of H. dilatata which displayed quorum sensing inhibitory activity were identified by GC/MS analysis. |
分子量 | 374.477 |
分子式 | C22H30O5 |
CAS No. | 111200-01-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
7-Ethoxyrosmanol 111200-01-2 Microbiology/Virology Antifection 7Ethoxyrosmanol 7 Ethoxyrosmanol Inhibitor inhibitor inhibit