| 规格 | 库存 | 单价 | 数量 |
|---|---|---|---|
| 5 mg | 上海现货 | 3660.00 |
|
| 10 mg | 上海现货 | 6210.00 |
|
| 25 mg | 上海现货 | 11178.00 |
|
生物活性
|
产品描述 |
6-Methoxyluteolin has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain. |
|
靶点活性 |
Calcium Channel, Histamine Receptor, |
|
体外活性 |
Using the human basophilic KU812F cells, we assessed the inhibitory effects of 6-Methoxyluteolin, isolated from Chrysanthemum zawadskii, in the FcαµRI-mediated allergic reaction. We determined that 6-Methoxyluteolin inhibited anti-FcαµRI α± chain antibody (CRA-1)-induced histamine release, as well as elevation of intracellular calcium concentration [Ca2+]i in a dose-dependent manner. Moreover, the inhibitory effects of 6-Methoxyluteolin on the cell surface expression and the mRNA level of the FcαµRI α± chain were determined by flow cytometric analysis and reverse transcription-polymerase chain reaction (RTPCR), respectively. |
|
体内活性 |
化学信息
|
分子量 |
316.26 |
|
分子式 |
C16H12O7 |
|
CAS |
520-11-6 |
|
溶解度 |
（ < 1 mg/ml refers to the product slightly soluble or insoluble ) |
|
储存条件 |
store at -80°C |
|
备注 |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. |
配制溶液
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.162 ml | 15.81 ml | 31.62 ml |
| 5 mM | 0.632 ml | 3.162 ml | 6.324 ml |
| 10 mM | 0.316 ml | 1.581 ml | 3.162 ml |
| 50 mM | 0.063 ml | 0.316 ml | 0.632 ml |
产品操作手册
