Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1-(2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one (Cochinchinenin A) 是龙血镇痛作用的物质基础。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 395 | 现货 | ||
5 mg | ¥ 933 | 现货 | ||
10 mg | ¥ 1,370 | 现货 | ||
25 mg | ¥ 2,290 | 现货 | ||
50 mg | ¥ 3,450 | 现货 | ||
100 mg | ¥ 4,900 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 985 | 现货 |
产品描述 | 1-(2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one (Cochinchinenin A) is the material basis for the analgesic effect of Dragons Blood. |
体外活性 | According to the operational definition of material basis for the efficacy of TCM established, the material basis of the modulation on the TTX-R sodium currents in DRG neurons of dragon??s blood was judged from the experimental results. The drug interaction equation of Greco et al. was used to assess the interaction of the three components extracted from dragon??s blood. This investigation demonstrated that dragon??s blood suppressed the peak TTX-R sodium currents in a dose-dependent way and affected the activations of TTX-R sodium currents. The effects of the combination of Cochinchinenin A, cochinchinenin B, and loureirin B were in good agreement with those of dragon??s blood. Although the three components used alone could modulate TTX-R sodium currents, the concentrations of the three components used alone were respectively higher than those used in combination when the inhibition rates on the TTX-R sodium currents of them used alone and in combination were the same. The combined effects of the three components were synergistic. |
别名 | 剑叶龙血素A, Cochinchinenin A |
分子量 | 286.32 |
分子式 | C17H18O4 |
CAS No. | 221696-69-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (174.63 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 3.4926 mL | 17.463 mL | 34.926 mL | 87.3149 mL |
5 mM | 0.6985 mL | 3.4926 mL | 6.9852 mL | 17.463 mL | |
10 mM | 0.3493 mL | 1.7463 mL | 3.4926 mL | 8.7315 mL | |
20 mM | 0.1746 mL | 0.8731 mL | 1.7463 mL | 4.3657 mL | |
50 mM | 0.0699 mL | 0.3493 mL | 0.6985 mL | 1.7463 mL | |
100 mM | 0.0349 mL | 0.1746 mL | 0.3493 mL | 0.8731 mL |
中药材名称 | 中药材拉丁名 | 性 | 味 | 归经 |
黄花蒿 | Artemisia annua Linn. | 寒 | 苦 | |
剑叶龙血树 | Dracaena cochinchinensis (Lour.) S. C. Chen | - | ― | |
毛莲蒿 | Artemisia vestita Wall. | 寒 | 苦 |
方剂名称 | 处方组成 | 剂型 | 处方来源 |
人中白丸 | 人中白,羚羊角,生地黄,当归,黄花蒿,银柴胡,鳖甲,阿胶,白术,白芍,熟地黄 | 丸剂 | 《嵩崖尊生》卷十一。 |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
1-(2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one 221696-69-1 Others 剑叶龙血素A 1(2,6dimethoxyphenyl)3(4hydroxyphenyl)propan1one Cochinchinenin A 1 (2,6 dimethoxyphenyl) 3 (4 hydroxyphenyl)propan 1 one Inhibitor inhibitor inhibit