首页 Apoptosis BCL 1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one
1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one
编号 TN5263     别名: Xanthohumol, Xanthohumol,
CAS 569-83-5     分子式 C21H22O5     分子量 354.4
靶点: AIF; Bcl-2; Caspase; HCV; HIV; NMDAR; p53; PARP; XIAP;
Xanthohumol has anti-hepatitis C virus, anti-carcinogenic, free radical-scavenging, and anti-inflammatory activities, it can inhibit HIV-1 induced cytopathic effects, the production of viral p24 antigen and reverse transcriptase in C8166 lymphocytes at non-cytotoxic concentration. Xanthohumol may play a role in improving cognitive flexability in young animals. Xanthohumol has beneficial effects on markers of metabolic syndrome, it lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.
选择批次  
纯度 98.00%
规格 库存 单价 数量
1 mg 待询 995.00
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生物活性

产品描述

Xanthohumol has anti-hepatitis C virus, anti-carcinogenic, free radical-scavenging, and anti-inflammatory activities, it can inhibit HIV-1 induced cytopathic effects, the production of viral p24 antigen and reverse transcriptase in C8166 lymphocytes at non-cytotoxic concentration. Xanthohumol may play a role in improving cognitive flexability in young animals. Xanthohumol has beneficial effects on markers of metabolic syndrome, it lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.

靶点活性

AIF,

Bcl-2,

Caspase,

HCV,

HIV,

NMDAR,

p53,

PARP,

XIAP,

体外活性

体内活性

化学信息

分子量

354.4

分子式

C21H22O5

CAS

569-83-5

溶解度

( < 1 mg/ml refers to the product slightly soluble or insoluble )

储存条件

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

备注

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

配制溶液

1 mg 5 mg 10 mg
1 mM 2.822 ml 14.108 ml 28.217 ml
5 mM 0.564 ml 2.822 ml 5.643 ml
10 mM 0.282 ml 1.411 ml 2.822 ml
50 mM 0.056 ml 0.282 ml 0.564 ml
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