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RAAS

RAAS

The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure and fluid and electrolyte balance, as well as systemic vascular resistance.
TargetMol
1 2 3 4 5 6
Cat. No. Product Name CAS No. Purity Chemical Structure
T7616 A 779
化合物A 779(3TFA)
159432-28-7
TargetMol Chemical Structure A 779
A 779 是一种 G 蛋白偶联受体 Mas 的有效拮抗剂,Mas 受体是Ang1-7 receptor,与传统的AngII 不同。
T7575 [Sar1, Ile8]-Angiotensin II
化合物[Sar1, Ile8]-Angiotensin II(3TFA)
37827-06-8
TargetMol Chemical Structure [Sar1, Ile8]-Angiotensin II
[Sar1, Ile8]-Angiotensin II 是一种在血管平滑肌细胞中有多种作用(如正常动脉的收缩,培养的细胞或病变血管的肥大或增生等)的多肽,。
T14123 ACT 178882
化合物 T14123
1007392-69-9 98%
TargetMol Chemical Structure ACT 178882
ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).
T16544 Pivalopril
化合物 T16544
81045-50-3 98%
TargetMol Chemical Structure Pivalopril
Pivalopril is a new orally active inhibitor of angiotensin-converting enzyme.
T11809 L162441
化合物 T11809
154512-46-6 98%
TargetMol Chemical Structure L162441
L162441 is an antagonist of Angiotensin type 1 receptor.
T10323 Angiotensin II (3-8), human TFA
化合物 T10323
T10323 98%
TargetMol Chemical Structure Angiotensin II (3-8), human TFA
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.
T16573 Pratosartan
化合物 T16573
153804-05-8 98%
TargetMol Chemical Structure Pratosartan
Pratosartan is a selective antagonist of angiotensin II receptor.
T19187 Aliskiren D6 hemifumarate
化合物 T19187
T19187 98%
TargetMol Chemical Structure Aliskiren D6 hemifumarate
Aliskiren (CGP 60536) D6 hemifumarate is a deuterium-labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: ...
T16385 Omapatrilat
化合物 T16385
167305-00-2 98%
TargetMol Chemical Structure Omapatrilat
Omapatrilat is a metalloprotease ACE and NEP dual inhibitor (Ki: 0.64 and 0.45 nM, respectively).
T6444 Cilazapril Monohydrate
西拉普利水合物
92077-78-6 98%
TargetMol Chemical Structure Cilazapril Monohydrate
Cilazapril Monohydrate (Justor) 是一种血管紧张素转化酶抑制剂,能够作用于高血压和充血性心力衰竭的研究。
T11808 L162389
化合物 T11808
169281-53-2 98%
TargetMol Chemical Structure L162389
L162389 is a potent angiotensin AT1 receptor antagonist with Ki of 28 nM.
T12704 Rentiapril
化合物 T12704
80830-42-8 98%
TargetMol Chemical Structure Rentiapril
Rentiapril is an orally active inhibitor of angiotensin converting enzyme (ACE), with antihypertensive activity.
TN4431 Leucosceptoside A
米团花苷A
83529-62-8 98%
TargetMol Chemical Structure Leucosceptoside A
Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidas...
TN1464 Camellianin A
山茶黄酮苷 A
109232-77-1 98%
TargetMol Chemical Structure Camellianin A
Camellianin A has anticancer activity, it can inhibit the proliferation of the human hepatocellular liver carcinoma Hep G2 and human breast adenocarcinoma MCF-7 ...
T5824 Angiotensin II (3-8), human
化合物Angiotensin IV
12676-15-2 98%
TargetMol Chemical Structure Angiotensin II (3-8), human
Angiotensin II (3-8), human 是活性稍弱的血管紧张素AT1受体激动剂。
T6627 Phosphoramidon Disodium
磷酰胺二钠
164204-38-0 98%
TargetMol Chemical Structure Phosphoramidon Disodium
Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt 是一种金属蛋白酶 (metalloprotease) 抑制剂 。Phosphoramidon Disodium Salt 抑制内皮素转化酶 (ECE) ,中性肽内切酶 (NEP) 和血管紧张素转换酶 (...
T11642 Imidaprilate
化合物 T11642
89371-44-8 98%
TargetMol Chemical Structure Imidaprilate
Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM). It is used in the research of the...
T2318 Sacubitril/Valsartan
沙库必曲/缬沙坦
936623-90-4 99.94%
TargetMol Chemical Structure Sacubitril/Valsartan
Sacubitril/Valsartan (LCZ696),以1:1摩尔比由Valsartan(一种ARB)和Sacubitril(AHU377)组成,为创新口服血管紧张素受体-脑啡肽酶(ARN)双重抑制剂,旨在治疗高血压与心力衰竭。其作用机制包括抑制炎症、氧化应激及细胞凋亡,有助于改善糖尿病心肌病。
T6542 Imidapril hydrochloride
盐酸咪达普利
89396-94-1 99.94%
TargetMol Chemical Structure Imidapril hydrochloride
Imidapril hydrochloride (Tanapril) 是一种血管紧张素转换酶 (ACE) 抑制剂,具有抗高血压活性。
T14939L CGP-42112 acetate
CGP-42112醋酸
99.92%
TargetMol Chemical Structure CGP-42112 acetate
CGP-42112 acetate是一种有效的血管紧张素受体 AT2 激动剂,抑制 LPS 产生的蛋白激酶 A 活性的增加。
A 779
T7616
A 779 是一种 G 蛋白偶联受体 Mas 的有效拮抗剂,Mas 受体是Ang1-7 receptor,与传统的AngII 不同。
[Sar1, Ile8]-Angiotensin II
T7575
[Sar1, Ile8]-Angiotensin II 是一种在血管平滑肌细胞中有多种作用(如正常动脉的收缩,培养的细胞或病变血管的肥大或增生等)的多肽,。
ACT 178882
T14123
ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).
Pivalopril
T16544
Pivalopril is a new orally active inhibitor of angiotensin-converting enzyme.
L162441
T11809
L162441 is an antagonist of Angiotensin type 1 receptor.
Angiotensin II (3-8), human TFA
T10323
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.
Pratosartan
T16573
Pratosartan is a selective antagonist of angiotensin II receptor.
Aliskiren D6 hemifumarate
T19187
Aliskiren (CGP 60536) D6 hemifumarate is a deuterium-labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: ...
Omapatrilat
T16385
Omapatrilat is a metalloprotease ACE and NEP dual inhibitor (Ki: 0.64 and 0.45 nM, respectively).
Cilazapril Monohydrate
T6444
Cilazapril Monohydrate (Justor) 是一种血管紧张素转化酶抑制剂,能够作用于高血压和充血性心力衰竭的研究。
L162389
T11808
L162389 is a potent angiotensin AT1 receptor antagonist with Ki of 28 nM.
Rentiapril
T12704
Rentiapril is an orally active inhibitor of angiotensin converting enzyme (ACE), with antihypertensive activity.
Leucosceptoside A
TN4431
Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidas...
Camellianin A
TN1464
Camellianin A has anticancer activity, it can inhibit the proliferation of the human hepatocellular liver carcinoma Hep G2 and human breast adenocarcinoma MCF-7 ...
Angiotensin II (3-8), human
T5824
Angiotensin II (3-8), human 是活性稍弱的血管紧张素AT1受体激动剂。
Phosphoramidon Disodium
T6627
Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt 是一种金属蛋白酶 (metalloprotease) 抑制剂 。Phosphoramidon Disodium Salt 抑制内皮素转化酶 (ECE) ,中性肽内切酶 (NEP) 和血管紧张素转换酶 (...
Imidaprilate
T11642
Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM). It is used in the research of the...
Sacubitril/Valsartan
T2318
Sacubitril/Valsartan (LCZ696),以1:1摩尔比由Valsartan(一种ARB)和Sacubitril(AHU377)组成,为创新口服血管紧张素受体-脑啡肽酶(ARN)双重抑制剂,旨在治疗高血压与心力衰竭。其作用机制包括抑制炎症、氧化应激及细胞凋亡,有助于改善糖尿病心肌病。
Imidapril hydrochloride
T6542
Imidapril hydrochloride (Tanapril) 是一种血管紧张素转换酶 (ACE) 抑制剂,具有抗高血压活性。
CGP-42112 acetate
T14939L
CGP-42112 acetate是一种有效的血管紧张素受体 AT2 激动剂,抑制 LPS 产生的蛋白激酶 A 活性的增加。
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TargetMol Loading
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