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VEGFB Protein, Human, Recombinant (hFc)

VEGFB Protein, Human, Recombinant (hFc)

产品编号 TMPY-04327
别名: VRF, 血管内皮生长因子, vascular endothelial growth factor B, VEGFL

Vascular endothelial growth factor-B (VEGF-B) is closely related to VEGF-A, an effector of blood vessel growth during development and disease and a strong candidate for angiogenic therapies. In detail, VEGFB can positively prevent the Ang II-induced rising in the size of cardiomyocyte as well as reduce Ang II-induced mRNA and protein levels of β-MHC (β-myosin heavy chain), BNP (brain natriuretic peptide), and ANP (atrial natriuretic peptide). Moreover, VEGFB can regulate the decline of the Ang II-induced rising in Ca2+.

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VEGFB Protein, Human, Recombinant (hFc)
规格 价格/CNY 货期 数量
20 μg ¥ 1,350 5日内发货
100 μg ¥ 3,430 5日内发货
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产品目录号及名称: VEGFB Protein, Human, Recombinant (hFc) (TMPY-04327)
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生物活性
技术参数
产品性质
生物活性 Measured by its binding ability in a functional ELISA. Immobilized human S4-Fc3L3-VEGFB at 10 μg/ml (100 μL/well) can bind biotinylated human NRP1-Fc , The EC50 of biotinylated human NRP1-Fc is 0.03-0.07μg/mL.
产品描述 Vascular endothelial growth factor-B (VEGF-B) is closely related to VEGF-A, an effector of blood vessel growth during development and disease and a strong candidate for angiogenic therapies. In detail, VEGFB can positively prevent the Ang II-induced rising in the size of cardiomyocyte as well as reduce Ang II-induced mRNA and protein levels of β-MHC (β-myosin heavy chain), BNP (brain natriuretic peptide), and ANP (atrial natriuretic peptide). Moreover, VEGFB can regulate the decline of the Ang II-induced rising in Ca2+.
种属 Human
表达系统 HEK293 Cells
标签 N-hFc
蛋白编号 P49765-1
别名 VRF, 血管内皮生长因子, vascular endothelial growth factor B, VEGFL
蛋白构建 The Human VEGFB (NP_003368.1) (Pro22-Ala207) was expressed with the Fc region of Human IgG1 at the N-terminus.
蛋白纯度 > 95 % as determined by SDS-PAGE
分子量 47.8 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Vascular endothelial growth factor-B (VEGF-B) is closely related to VEGF-A, an effector of blood vessel growth during development and disease and a strong candidate for angiogenic therapies. In detail, VEGFB can positively prevent the Ang II-induced rising in the size of cardiomyocyte as well as reduce Ang II-induced mRNA and protein levels of β-MHC (β-myosin heavy chain), BNP (brain natriuretic peptide), and ANP (atrial natriuretic peptide). Moreover, VEGFB can regulate the decline of the Ang II-induced rising in Ca2+.

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Keywords

VEGFB Protein, Human, Recombinant (hFc) VRF 血管内皮生长因子 vascular endothelial growth factor B VEGFL recombinant recombinant-proteins proteins protein

 

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