ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc)

ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-110 KDa and the accession number is P14719-2.

规格	价格/CNY		数量
10 μg	￥ 740	5日内发货
50 μg	￥ 1,970	5日内发货
500 μg	￥ 12,100	5日内发货
1 mg	￥ 17,400	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 740

5日内发货

50 μg

￥ 1,970

5日内发货

500 μg

￥ 12,100

5日内发货

1 mg

￥ 17,400

5日内发货

生物活性	1. Loaded Human IL-33 on AR2G Biosensor, can bind Mouse ST2-Fc with an affinity constant of 2.28nM as determined in BLI assay. (Regularly tested) 2. Immobilized Mouse IL-33 at 5μg/ml (100 μl/well) can bind Mouse ST2-Fc. The ED50 of Mouse ST2-Fc is 0.25 ug/ml. (Regularly tested)
产品描述	ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-110 KDa and the accession number is P14719-2.

种属	Mouse
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	P14719-2
别名	Protein ST2, IL-1 R4, IL-33R, ST2V, suppression of tumorigenicity 2, ST2L, Il1rl1, DER4, Ly84, IL-1RL1, Fit-1, Lymphocyte antigen 84, Protein T1, Interleukin-1 receptor-like 1
氨基酸序列	Ser27-Ala337
蛋白构建	Ser27-Ala337 (Val192Ala)
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	90-110 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor α chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33, enhances inflammatory cytokines by activating nuclear factor-κB (NF-κB) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process, while sST2 can suppress IL-33 activity.

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ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc)

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