Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His)

Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-120 KDa and the accession number is AAA02562.1.

规格	价格/CNY		数量
10 μg	￥ 450	5日内发货
50 μg	￥ 1,370	5日内发货
500 μg	￥ 11,700	5日内发货
1 mg	￥ 17,600	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 450

5日内发货

50 μg

￥ 1,370

5日内发货

500 μg

￥ 11,700

5日内发货

1 mg

￥ 17,600

5日内发货

产品描述	Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-120 KDa and the accession number is AAA02562.1.

种属	Mouse
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	AAA02562.1
别名	CD22 antigenMGC130020, B-cell receptor CD22, B-lymphocyte cell adhesion molecule, SIGLEC2FLJ22814, T-cell surface antigen Leu-14, CD22 molecule, Siglec-2, sialic acid binding Ig-like lectin 2, BL-CAM, CD22
氨基酸序列	Ser22-Arg702
蛋白构建	Ser22-Arg702
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	100-120 KDa, reducing conditions

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Human Siglec-2, also known as B-cell antigen CD22 or B-lymphocyte cell adhesion molecule (BL-CAM), is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells. Two distinct human Siglec-2/CD22 cDNAs that arise from differential RNA processing of the same gene have been isolated. Siglec-2/CD22 is an adhesion molecule that preferentially binds alpha 2,6- linked sialic acid on the same (cis) or adjacent (trans) cells. Interaction of CD22 with trans ligands on opposing cells was found to be favored over the binding of ligands in cis.

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Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His)

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