Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc)

Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 80-90 KDa and the accession number is L0N6D9.

规格	价格/CNY		数量
10 μg	￥ 550	5日内发货
50 μg	￥ 1,670	5日内发货
500 μg	￥ 13,700	5日内发货
1 mg	￥ 20,500	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 550

5日内发货

50 μg

￥ 1,670

5日内发货

500 μg

￥ 13,700

5日内发货

1 mg

￥ 20,500

5日内发货

生物活性	1. Loaded Anti-Human Nectin-4 mAb-mFc on AMQ Biosensor, can bind Cynomolgus Nectin-4-Fc with an affinity constant of 1.02 nM as determined in BLI assay. (Regularly tested) 2. Immobilized Anti-Human Nectin-4 mAb-mFc at 2μg/ml (100 μl/well) can bind Cynomolgus Nectin-4-Fc. The ED50 of Cynomolgus Nectin-4-Fc is 4.93 ng/ml. (Regularly tested)
产品描述	Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 80-90 KDa and the accession number is L0N6D9.

种属	Cynomolgus
表达系统	Human Cells
标签	C-Fc
蛋白编号	L0N6D9
别名	PRR4, Ig superfamily receptor LNIR, PVRL4, Poliovirus receptor-related protein 4, Nectin-4, LNIR
氨基酸序列	Gly32-Ser349
蛋白构建	Recombinant Cynomolgus Poliovirus Receptor-Related Protein 4 is produced by our Mammalian expression system and the target gene encoding Gly32-Ser349 is expressed with a human IgG1 Fc tag at the C-terminus.
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	80-90 KDa, reducing conditions

内毒素	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a 0.2 μm filtered solution of 20m PB,150mM NaCl, pH 7.4.
复溶方法	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
存储	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输方式	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
研究背景	Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.

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Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc)

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