购物车
VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc)

VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc)

产品编号 TMPY-03155
别名: vascular endothelial growth factor C

VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 41.5 kDa and the accession number is O35757.

TargetMol的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。
TargetMol
VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc)
规格 价格/CNY 货期 数量
50 μg ¥ 2,940 5日内发货
药物设计专题培训
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
产品目录号及名称: VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc) (TMPY-03155)
点击图片重新获取验证码
更多批次查询请联系客服
生物活性
技术参数
产品性质
参考文献
生物活性 1. Immobilized mouse FLT4-His at 10 μg/mL (100 μL/well) can bind mouse/rat Fc-VEGFC, The EC50 of mouse/rat Fc-VEGFC is 0.41-0.95 μg/mL. 2. Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 70-300 ng/mL.
产品描述 VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 41.5 kDa and the accession number is O35757.
种属 Mouse,Rat
表达系统 HEK293 Cells
标签 N-hFc
蛋白编号 O35757
别名 vascular endothelial growth factor C
蛋白构建 The Mouse / Rat VEGFC (NP_033532.1/O35757) (Ala108-Arg223) was expressed fused with the Fc region of Human IgG1 at the N-terminus. Mouse and Rat mature VEGFC sequences are identical.
蛋白纯度 > 90 % as determined by SDS-PAGE
分子量 41.5 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotein, as a ligand for two receptors, VEGFR-3 (Flt4), and VEGFR-2. VEGF-C may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis. VEGF-C protein is over-expressed in various human cancers including breast cancer and prostate cancer. VEGF-C/VEGFR-3 axis, through different signaling pathways, plays a critical role in cancer progression by regulating different cellular functions, such as invasion, proliferation, and resistance to chemotherapy. Thus, targeting the VEGF-C/VEGFR-3 axis may be therapeutically significant for certain types of tumors.

TargetMol Library Books参考文献

TargetMol Protein Calculator计算器

复溶计算器
重组蛋白稀释计算器
比活力计算器
=
÷
X
=
X
(Unit/mg)
= 106 ÷
ng/mL

bottom

技术支持

您可能有的问题的答案可以在重组蛋白操作手册中找到

Keywords

VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc) vascular endothelial growth factor C recombinant recombinant-proteins proteins protein

 

TargetMol Loading
陶术
生物
TargetMol®中国区唯一合作伙伴
点击进入陶术生物官网陶术生物
联系我们
400-820-0310

上海市静安区江场三路238号8楼