Kallikrein 2/KLK2 Protein, Human, Recombinant (His)

Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. KLK2 is inhibited by serpins such as protein C inhibitor, antichymotrypsin, and plasminogen. KLK2 is considered to be a biomarker for prostate cancer.

规格	价格/CNY		数量
10 μg	￥ 1,170	5日内发货
50 μg	￥ 3,470	5日内发货
500 μg	￥ 13,200	5日内发货
1 mg	￥ 18,900	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 1,170

5日内发货

50 μg

￥ 3,470

5日内发货

500 μg

￥ 13,200

5日内发货

1 mg

￥ 18,900

5日内发货

产品描述

种属	Human
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	P20151
别名	hGK-1, Kallikrein-2, Tissue Kallikrein-2, KLK2, Glandular Kallikrein-1
氨基酸序列	Pro19-Pro261
蛋白构建	Pro19-Pro261
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
分子量	(10-12)&(16-19)&(28-33) KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Supplied as a 0.2 μm filtered solution of 20 mM Acetate, 250 mM Trehalose, 0.02% Tween 80, pH5.0.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-\|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-\|-Xaa or Leu-\|-Xaa. KLK2 is inhibited by serpins such as protein C inhibitor, antichymotrypsin, and plasminogen. KLK2 is considered to be a biomarker for prostate cancer.

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Kallikrein 2/KLK2 Protein, Human, Recombinant (His)

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