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IL-23R Protein, Canine, Recombinant (His)

IL-23R Protein, Canine, Recombinant (His)

产品编号 TMPK-00575
别名: IBD17, IL-23 R, IL-23 receptor

IL-23R Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.31 kDa and the accession number is A0A8I3PXL0.

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IL-23R Protein, Canine, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 3,100 5日内发货
500 μg ¥ 12,400 5日内发货
1 mg ¥ 20,700 5日内发货
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产品目录号及名称: IL-23R Protein, Canine, Recombinant (His) (TMPK-00575)
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生物活性
技术参数
产品性质
参考文献
生物活性 Immobilized Canine IL-23R, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-23 alpha&IL-12 beta, His Tag with the EC50 of 1.95μg/ml determined by ELISA.
产品描述 IL-23R Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.31 kDa and the accession number is A0A8I3PXL0.
种属 Canine
表达系统 HEK293 Cells
标签 C-His
蛋白编号 A0A8I3PXL0
别名 IBD17, IL-23 R, IL-23 receptor
蛋白构建 Gly24-Asp354
蛋白纯度 > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量 39.31 kDa (predicted). Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
内毒素 < 1 EU/μg by the LAL method.
缓冲液 Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
存储

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The functional IL-23 receptor complex consists of two receptor subunits, the IL-12 receptor beta 1 subunit (IL-12 R beta 1) and the IL-23-specific receptor subunit (IL-23 R).This receptor associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade.

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Keywords

IL-23R Protein, Canine, Recombinant (His) IBD17 IL-23 R IL-23 receptor IBD 17 IBD-17 recombinant recombinant-proteins proteins protein

 

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