SARS-CoV-2 Guanine-N7 methyltransferase Protein (His)

The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and dsRNA in a 3' to 5' direction and a N7-guanine methyltransferase activity. It may be involved in the proof-reading ability during the viral RNA replication and transcription. GTP, dGTP as well as cap analogs GpppG, GpppA and m7GpppG could be methylated by nsp14.

规格	价格/CNY		数量
10 μg	￥ 1,170	5日内发货
50 μg	￥ 3,550	5日内发货
500 μg	￥ 18,900	5日内发货
1 mg	￥ 28,500	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 1,170

5日内发货

50 μg

￥ 3,550

5日内发货

500 μg

￥ 18,900

5日内发货

1 mg

￥ 28,500

5日内发货

产品描述

种属	SARS-CoV-2
表达系统	E. coli
标签	N-6xHis
蛋白编号	YP_009725309.1
别名	SARS-CoV 2 nsp14, Guanine-N7 methyltransferase, SARS-CoV 2 ExoN
氨基酸序列	Ala1-Gln527
蛋白构建	Ala1-Gln527
分子量	60 KDa (reducing condition)

缓冲液	Supplied as a 0.2 μm filtered solution of 20 mM PB, 100 mM NaCl, 2 mM DTT, 20% Glycerol, 0.1% TritonX-100, pH 6.0.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and dsRNA in a 3' to 5' direction and a N7-guanine methyltransferase activity. It may be involved in the proof-reading ability during the viral RNA replication and transcription. GTP, dGTP as well as cap analogs GpppG, GpppA and m7GpppG could be methylated by nsp14.

计算器

复溶计算器

重组蛋白稀释计算器

比活力计算器

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

bottom

SARS-CoV-2 Guanine-N7 methyltransferase Protein (His)

计算器

技术支持

Keywords