GPC3 Protein, Rhesus macaque, Recombinant (His)

GPC3 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38 and 65-120 KDa and the accession number is XP_005594665.1.

规格	价格/CNY		数量
10 μg	￥ 710	5日内发货
50 μg	￥ 2,160	5日内发货
500 μg	￥ 14,200	5日内发货
1 mg	￥ 21,300	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 710

5日内发货

50 μg

￥ 2,160

5日内发货

500 μg

￥ 14,200

5日内发货

1 mg

￥ 21,300

5日内发货

产品描述	GPC3 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38 and 65-120 KDa and the accession number is XP_005594665.1.

种属	Rhesus
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	XP_005594665.1
别名	OCI5, GPC3, Glypican-3, MXR7, Intestinal protein OCI-5, GTR2-2
氨基酸序列	Gln25-His559
蛋白构建	Gln25-His559
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	38&65-120 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 5% Trehalose, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Glypican-3/GPC3 is a member of the glypican family. It belongs to the glypican family and is highly expressed in lung, liver, and kidney. It is a heparan sulfate proteoglycan, which is overexpressed in various neoplasms such as hepatocellular carcinoma, malignant melanoma, and testicular yolk sac tumor, and plays an important role in cell growth and differentiation. GPC3 function is tissue dependent. In some tissues, GPC3 acts as a tumor suppressor gene, whereas in others, it acts as an oncofetal protein. GPC3 is a reliable marker for hepatocellular carcinoma. The sensitivity and specificity exceeds both alpha-fetoprotein and hepatocyte-paraffin1. GPC3 immunohistochemistry can aid in the differentiation of testicular germ cell tumors, being expressed in all yolk sac tumors but not in seminomas. GPC3 expression has also been identified in some squamous cell carcinomas of the lung and clear cell carcinomas of the ovary. Glypican-3 is currently regarded as a tumor marker and potential target for immunotherapy.

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GPC3 Protein, Rhesus macaque, Recombinant (His)

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