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FGF-21 Protein, Human, Recombinant (His)

FGF-21 Protein, Human, Recombinant (His)

产品编号 TMPY-01889
别名: 成纤维细胞生长因子, UNQ3115 / PRO10196, fibroblast growth factor 21

FGF-21 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 20.2 kDa and the accession number is A0A7U3L5M7.

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FGF-21 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
50 μg ¥ 1,950 5日内发货
1 mg ¥ 19,100 5日内发货
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产品目录号及名称: FGF-21 Protein, Human, Recombinant (His) (TMPY-01889)
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生物活性
技术参数
产品性质
参考文献
生物活性 Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is typically 0.1-­1 µg/mL in the presence of 2.5 µg/mL of rmKlotho β.
产品描述 FGF-21 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 20.2 kDa and the accession number is A0A7U3L5M7.
种属 Human
表达系统 E. coli
标签 N-His
蛋白编号 A0A7U3L5M7
别名 成纤维细胞生长因子, UNQ3115 / PRO10196, fibroblast growth factor 21
蛋白构建 The mature form of Human FGF21 (NP_061986.1) (His 29-Ser 209) was expressed, with a polyhistide tag at the N-terminus.
蛋白纯度 > 95 % as determined by SDS-PAGE
分子量 20.2 kDa (predicted)
内毒素 Please contact us for more information.
缓冲液 Lyophilized from 50 mM Tris, 10% glycerol, 0.05% Brij 35, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic properties in animal models of diabetes and obesity. FGF21 is a novel adipokine associated with obesity-related metabolic complications in humans. The paradoxical increase of serum FGF21 in obese individuals, which may be explained by a compensatory response or resistance to FGF21, warrants further investigation. FGF-21, which we have identified as a novel metabolic factor, exhibits the therapeutic characteristics necessary for an effective treatment of diabetes.

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Keywords

FGF-21 Protein, Human, Recombinant (His) UNQ3115 / PRO 10196 UNQ3115 / PRO-10196 成纤维细胞生长因子 UNQ3115 / PRO10196 fibroblast growth factor 21 recombinant recombinant-proteins proteins protein

 

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