Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is P03953-1.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 3,400 | 5日内发货 | ||
500 μg | ¥ 13,600 | 5日内发货 | ||
1 mg | ¥ 22,700 | 5日内发货 |
产品描述 | Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is P03953-1. |
种属 | Mouse |
表达系统 | HEK293 |
标签 | C-hFc |
蛋白编号 | P03953-1 |
别名 | C3 convertase activator, AMBP-1, PFD, FACTOR D, CFD, ADN, EC 3.4.21.46, Complement factor D, DF, EC 3.4.21, Adipsin |
蛋白构建 | Recombinant Mouse Complement Factor D/CFD Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Ile26-Ser259.[Accession |P03953-1] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | The protein has a predicted MW of 52.2 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Supplied as 0.22μm filtered solution in 20mM Tris,500mM NaCl (pH 7.4). |
存储 |
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. |
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Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) C3 convertase activator AMBP-1 PFD AMBP1 FACTOR D AMBP 1 CFD ADN EC 3.4.21.46 Complement factor D DF EC 3.4.21 Adipsin recombinant recombinant-proteins proteins protein